ID   A0A1Q2MCX4_9BACT        Unreviewed;       959 AA.
AC   A0A1Q2MCX4;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Mannosylglycerate hydrolase {ECO:0000313|EMBL:AQQ70157.1};
DE            EC=3.2.1.170 {ECO:0000313|EMBL:AQQ70157.1};
GN   Name=mngB_3 {ECO:0000313|EMBL:AQQ70157.1};
GN   ORFNames=SMSP2_00499 {ECO:0000313|EMBL:AQQ70157.1};
OS   Limihaloglobus sulfuriphilus.
OC   Bacteria; Planctomycetota; Phycisphaerae; Sedimentisphaerales;
OC   Sedimentisphaeraceae; Limihaloglobus.
OX   NCBI_TaxID=1851148 {ECO:0000313|EMBL:AQQ70157.1, ECO:0000313|Proteomes:UP000188181};
RN   [1] {ECO:0000313|Proteomes:UP000188181}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SM-Chi-D1 {ECO:0000313|Proteomes:UP000188181};
RA   Spring S., Bunk B., Sproer C.;
RT   "Comparative genomics and description of representatives of a novel lineage
RT   of planctomycetes thriving in anoxic sediments.";
RL   Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 38 family.
CC       {ECO:0000256|ARBA:ARBA00009792}.
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DR   EMBL; CP019646; AQQ70157.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Q2MCX4; -.
DR   STRING; 1851148.SMSP2_00499; -.
DR   KEGG; pbas:SMSP2_00499; -.
DR   OrthoDB; 9772207at2; -.
DR   Proteomes; UP000188181; Chromosome.
DR   GO; GO:0004559; F:alpha-mannosidase activity; IEA:InterPro.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006013; P:mannose metabolic process; IEA:InterPro.
DR   Gene3D; 3.20.110.10; Glycoside hydrolase 38, N terminal domain; 1.
DR   Gene3D; 1.20.1270.50; Glycoside hydrolase family 38, central domain; 1.
DR   Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR   InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR   InterPro; IPR011330; Glyco_hydro/deAcase_b/a-brl.
DR   InterPro; IPR011682; Glyco_hydro_38_C.
DR   InterPro; IPR015341; Glyco_hydro_38_cen.
DR   InterPro; IPR037094; Glyco_hydro_38_cen_sf.
DR   InterPro; IPR000602; Glyco_hydro_38_N.
DR   InterPro; IPR027291; Glyco_hydro_38_N_sf.
DR   InterPro; IPR028995; Glyco_hydro_57/38_cen_sf.
DR   InterPro; IPR013780; Glyco_hydro_b.
DR   PANTHER; PTHR46017; ALPHA-MANNOSIDASE 2C1; 1.
DR   PANTHER; PTHR46017:SF2; MANNOSYLGLYCERATE HYDROLASE; 1.
DR   Pfam; PF09261; Alpha-mann_mid; 1.
DR   Pfam; PF07748; Glyco_hydro_38C; 1.
DR   Pfam; PF01074; Glyco_hydro_38N; 1.
DR   SMART; SM00872; Alpha-mann_mid; 1.
DR   SUPFAM; SSF88688; Families 57/38 glycoside transferase middle domain; 1.
DR   SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR   SUPFAM; SSF88713; Glycoside hydrolase/deacetylase; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000313|EMBL:AQQ70157.1};
KW   Hydrolase {ECO:0000313|EMBL:AQQ70157.1};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000188181}.
FT   DOMAIN          335..409
FT                   /note="Glycoside hydrolase family 38 central"
FT                   /evidence="ECO:0000259|SMART:SM00872"
SQ   SEQUENCE   959 AA;  108706 MW;  B2E3ED2A4BAAA21C CRC64;
     MASKKTVHVI SGTHWDREWR FTADQSLLRL AELVDELLDI LEANPDYKCF LLDGGTVVIE
     DYLNVRPENE QRLRDFMSAG RIETVMWYTL PEMSTVAPEA LVRNLLIGKR IAAKFGGCIN
     AGYTATSYGQ ISQLAQIYAG FGTRSALSYR GTNKQQVPPI CKLESPDGTQ IYHIRCFDEV
     TRTNWFFFPH YMLVLGKAPR DLSTKWNPAE WPVHMADDAL YQSAFQMKNE SMEFNRDPET
     IRKAARMLGA QAEPQMINNQ LLALDMEDNA VPYQRLPEMI QAINKAQDEY LIKQSSLDEY
     VEACVEGLDP DTVPVHIGEM RYTLIEAGFN GLLGATHSSR INLKLLNDLA QRELINTAEP
     LSAMSSMLGG SYESSLLHRA WLYLLKNHAH DSICGAAIDE AHKDNPFRFR AATSIARECS
     RKACEQIWAK MDTQSGFQEK DVTLTFFNTL PISRKRVEHV VVDVPRPDFG AFKIEPCTGV
     GPIVEGFNPD DMLTFQYFDI VDQDGNKIKY EILDRENIDL EVERKLDTNA AVYDIQRNRL
     LIEVELPAMG YKTYAVRPRK REYNPEPKPA GERGLIASQK GVLENEHLRV QINSDGTFNI
     LNKKTAEYSE RLHYFCDDAS TGNAHKHKGT LRDFTVTSLG CNSIITLIEN NTLRATWKVE
     LAMMIPDRAD HAARDRSHSR VELPVEMYLT LRKDSNALEI KTVIENTAKD HRLRIMMPTG
     VKTDYAYADG PFDVLKRSLL WDDTKDNMEE YHPYKPMQRF VTLSDDSRGF SFISKGLGEY
     EVIDDSDRTL AITLMRTSRA YMRANRGVMT PAEYEQNLGQ HLIGIGKLEF EYAIYPHEGD
     WRQAGVHLVS DDFRGPVRVL QGVPKAGELS AEQSLIQISP AESMQVSAFF WSRESKGYIL
     RLWNAAETSV EAKIKLAADF SNAAIVSLDE ERIEQNLDIS GGSVAFNVPK SRIVTLLLK
//