ID A0A1Q2MFU2_9BACT Unreviewed; 425 AA.
AC A0A1Q2MFU2;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=UDP-N-acetyl-D-glucosamine 6-dehydrogenase {ECO:0000313|EMBL:AQQ71519.1};
DE EC=1.1.1.136 {ECO:0000313|EMBL:AQQ71519.1};
GN Name=wbpA {ECO:0000313|EMBL:AQQ71519.1};
GN ORFNames=SMSP2_01893 {ECO:0000313|EMBL:AQQ71519.1};
OS Limihaloglobus sulfuriphilus.
OC Bacteria; Planctomycetota; Phycisphaerae; Sedimentisphaerales;
OC Sedimentisphaeraceae; Limihaloglobus.
OX NCBI_TaxID=1851148 {ECO:0000313|EMBL:AQQ71519.1, ECO:0000313|Proteomes:UP000188181};
RN [1] {ECO:0000313|Proteomes:UP000188181}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SM-Chi-D1 {ECO:0000313|Proteomes:UP000188181};
RA Spring S., Bunk B., Sproer C.;
RT "Comparative genomics and description of representatives of a novel lineage
RT of planctomycetes thriving in anoxic sediments.";
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the UDP-glucose/GDP-mannose dehydrogenase
CC family. {ECO:0000256|PIRNR:PIRNR000124}.
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DR EMBL; CP019646; AQQ71519.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Q2MFU2; -.
DR STRING; 1851148.SMSP2_01893; -.
DR KEGG; pbas:SMSP2_01893; -.
DR OrthoDB; 9803238at2; -.
DR Proteomes; UP000188181; Chromosome.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0047004; F:UDP-N-acetylglucosamine 6-dehydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR017476; UDP-Glc/GDP-Man.
DR InterPro; IPR014027; UDP-Glc/GDP-Man_DH_C.
DR InterPro; IPR036220; UDP-Glc/GDP-Man_DH_C_sf.
DR InterPro; IPR014026; UDP-Glc/GDP-Man_DH_dimer.
DR InterPro; IPR001732; UDP-Glc/GDP-Man_DH_N.
DR InterPro; IPR028359; UDP_ManNAc/GlcNAc_DH.
DR NCBIfam; TIGR03026; NDP-sugDHase; 1.
DR PANTHER; PTHR43491; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR PANTHER; PTHR43491:SF1; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR Pfam; PF00984; UDPG_MGDP_dh; 1.
DR Pfam; PF03720; UDPG_MGDP_dh_C; 1.
DR Pfam; PF03721; UDPG_MGDP_dh_N; 1.
DR PIRSF; PIRSF500136; UDP_ManNAc_DH; 1.
DR PIRSF; PIRSF000124; UDPglc_GDPman_dh; 1.
DR SMART; SM00984; UDPG_MGDP_dh_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52413; UDP-glucose/GDP-mannose dehydrogenase C-terminal domain; 1.
PE 3: Inferred from homology;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:AQQ71519.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000188181}.
FT DOMAIN 316..414
FT /note="UDP-glucose/GDP-mannose dehydrogenase C-terminal"
FT /evidence="ECO:0000259|SMART:SM00984"
SQ SEQUENCE 425 AA; 47327 MW; 8E65CFCE9C5C728B CRC64;
MQVGIVGLGY VGLPLAREFV GGGVDVIGFD INDVNVKRIN AGKSPLKHIP DEHVSEMAKS
KLFKATTDMK QLSKPDAILI CVPTPLTENR EPDMTYVATT CETISKYLRK GQLVVLESTT
YPGTTRELMQ PILEKSGLKA GKDFYMAYSP EREDPGNKSF RTGTIAKVVG GLDKKSLDMA
MEVYRPAIEH LVPVSSCDVA EAAKIVENTY RCINIAMVNE LKMLFDRMGI DVWEVIDAAK
TKPFGFQAFY PGPGLGGHCI PIDPFYLTWR ARQYGMPTKF IELAGEINTD MPSYVVARTM
DALNEHKKSL KGSKVLLLGL AYKKDIDDVR ESPSMELIEL LVDKGAKVDY NDPYIPKTPK
MRMYNLGMKS KPLTEKSLAG YDAVLIATDH SDYDYKWIVK NAKLVVDTRN ATKEVKTGRK
KIFKA
//
