ID A0A1Q2SPC6_9GAMM Unreviewed; 468 AA.
AC A0A1Q2SPC6;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=Lipopolysaccharide export system protein LptA {ECO:0000256|HAMAP-Rule:MF_01914};
GN Name=lptA {ECO:0000256|HAMAP-Rule:MF_01914};
GN ORFNames=TAO_1620 {ECO:0000313|EMBL:BAW80990.1};
OS Candidatus Nitrosoglobus terrae.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales; Chromatiaceae;
OC Candidatus Nitrosoglobus.
OX NCBI_TaxID=1630141 {ECO:0000313|EMBL:BAW80990.1, ECO:0000313|Proteomes:UP000243679};
RN [1] {ECO:0000313|EMBL:BAW80990.1, ECO:0000313|Proteomes:UP000243679}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TAO100 {ECO:0000313|EMBL:BAW80990.1,
RC ECO:0000313|Proteomes:UP000243679};
RX PubMed=28072419; DOI=10.1038/ismej.2016.191;
RA Hayatsu M., Tago K., Uchiyama I., Toyoda A., Wang Y., Shimomura Y.,
RA Okubo T., Kurisu F., Hirono Y., Nonaka K., Akiyama H., Itoh T., Takami H.;
RT "An acid-tolerant ammonia-oxidizing ?-proteobacterium from soil.";
RL ISME J. 11:1130-1141(2017).
CC -!- FUNCTION: Involved in the assembly of lipopolysaccharide (LPS).
CC Required for the translocation of LPS from the inner membrane to the
CC outer membrane. May form a bridge between the inner membrane and the
CC outer membrane, via interactions with LptC and LptD, thereby
CC facilitating LPS transfer across the periplasm. {ECO:0000256|HAMAP-
CC Rule:MF_01914}.
CC -!- SUBUNIT: Component of the lipopolysaccharide transport and assembly
CC complex. {ECO:0000256|HAMAP-Rule:MF_01914}.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000256|HAMAP-Rule:MF_01914}.
CC -!- SIMILARITY: Belongs to the LptA family. {ECO:0000256|HAMAP-
CC Rule:MF_01914}.
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DR EMBL; AP014836; BAW80990.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Q2SPC6; -.
DR KEGG; ntt:TAO_1620; -.
DR OrthoDB; 9795964at2; -.
DR Proteomes; UP000243679; Chromosome.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR GO; GO:0001530; F:lipopolysaccharide binding; IEA:InterPro.
DR GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR GO; GO:0015920; P:lipopolysaccharide transport; IEA:UniProtKB-UniRule.
DR Gene3D; 2.60.450.10; Lipopolysaccharide (LPS) transport protein A like domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 3.
DR HAMAP; MF_01914; LPS_assembly_LptA; 1.
DR InterPro; IPR014340; LptA.
DR InterPro; IPR005653; OstA-like_N.
DR NCBIfam; TIGR03002; outer_YhbN_LptA; 1.
DR PANTHER; PTHR36504; LIPOPOLYSACCHARIDE EXPORT SYSTEM PROTEIN LPTA; 1.
DR PANTHER; PTHR36504:SF1; LIPOPOLYSACCHARIDE EXPORT SYSTEM PROTEIN LPTA; 1.
DR Pfam; PF03968; LptD_N; 1.
PE 3: Inferred from homology;
KW Periplasm {ECO:0000256|ARBA:ARBA00022764, ECO:0000256|HAMAP-Rule:MF_01914};
KW Reference proteome {ECO:0000313|Proteomes:UP000243679};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|HAMAP-Rule:MF_01914}.
FT DOMAIN 36..145
FT /note="Organic solvent tolerance-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF03968"
FT REGION 151..210
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 279..306
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 170..210
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 468 AA; 53079 MW; FD6B4ADD70FFAE1F CRC64;
MPQQISLRLI IFWLITQNLA YETALAFSND SGQPIHIEAD RGELDNRKQV AIYYGNVHLT
QDNLRIDSDT LTIFYTPEKK IKKAIAEGQP AWYRQQSNDD SEDMRAKALK IEYHADNATI
YLFQKAHVWQ GTNEFTGDRI VYDTEHRIVR GQGSKAGSGR VHVTIRPDEV EPSPNNSNST
PKNSDSTPSL AAPPKNQVAD NQQLKSGEDQ GRTTDWLALY DSANIKSNQI ILLQPRTQVT
IINRKDEWLH ITTLIKGELL EGWVEKKFIR LPESNTDSIS SSPIPIESSK NQVVKNQKSE
SRQAQNRTTD WLNLYASTDI KSNKVARLQP QTQVTIIDRK DEWLYITALV EGELLEGWAE
KKFIQLPETS MNSTHPSPIP IESSKNQIVK NQKIEIGQDR GRTADWLSLY ASANIKSNKV
ALLQPHTQIT IIDRKGAWIY LTALVEGELL EGWAEGRFIQ LLESSQPK
//
