ID A0A1Q2YFL7_9ASCO Unreviewed; 941 AA.
AC A0A1Q2YFL7;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=PX domain-containing protein {ECO:0000259|PROSITE:PS50195};
GN ORFNames=PMKS-001795 {ECO:0000313|EMBL:GAV28324.1};
OS Pichia membranifaciens.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Pichiaceae; Pichia.
OX NCBI_TaxID=4926 {ECO:0000313|EMBL:GAV28324.1, ECO:0000313|Proteomes:UP000186136};
RN [1] {ECO:0000313|EMBL:GAV28324.1, ECO:0000313|Proteomes:UP000186136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KS47-1 {ECO:0000313|EMBL:GAV28324.1,
RC ECO:0000313|Proteomes:UP000186136};
RA Konishi M., Ishida M., Arakawa T., Kato Y., Horiuchi J.;
RT "Whole genome shotgun sequence of Pichia membranifaciens KS47-1.";
RL Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAV28324.1}.
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DR EMBL; BDGI01000066; GAV28324.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Q2YFL7; -.
DR Proteomes; UP000186136; Unassembled WGS sequence.
DR GO; GO:0043226; C:organelle; IEA:UniProt.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR Gene3D; 1.10.167.10; Regulator of G-protein Signalling 4, domain 2; 1.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR036305; RGS_sf.
DR InterPro; IPR044926; RGS_subdomain_2.
DR InterPro; IPR013937; Sorting_nexin_C.
DR PANTHER; PTHR22775; SORTING NEXIN; 1.
DR PANTHER; PTHR22775:SF3; SORTING NEXIN-13; 1.
DR Pfam; PF08628; Nexin_C; 1.
DR Pfam; PF00787; PX; 1.
DR SMART; SM00312; PX; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR SUPFAM; SSF48097; Regulator of G-protein signaling, RGS; 1.
DR PROSITE; PS50195; PX; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000186136}.
FT DOMAIN 573..694
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT REGION 196..215
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 421..488
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 745..774
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 497..531
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 445..479
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 752..767
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 941 AA; 107951 MW; 672194C76FD60FB5 CRC64;
MKDRNNVKRF RNVLRRHSMS FNNLALPASE VNDILQFKVS IDNSKHDFEK ILQMVERSTD
KQSLLKYKYY ILLRNEKLLR LNPNLQIEES KTMQKYSKRC HTLLDAINLR MKEIGEGEEM
REVDTETRST TDRLEFLPQK SLVKDLSLHE ILSSPTRLKY FTSYMQLRGN RQALLDFWLS
AEGLRNPLEY NSVQAKPSLT HVNNNEEDDE SSDDEATTFV DNELTQAEDI KKIFTTYFNL
PVMKIPPKIF YKVSEFIEGN CTSILAYYRA RKSILKLQDF EYIRMKKSDF VAFKASDTWL
KLLVEEAVSI DHKSVKESID VLTDNADSER HISKNVNTSL KNTDKISGDP LAKYSEKEND
GNYVDVNMTG KVSDKVVKAV EDALNEIMKD SNKSDVDLSV SNDKRNSRLV SDDVARDLFG
SGEKSLFGDD EEEGEEGKSL EGQDDKCTTG INTHSSTDLD GDTVVSLNQD NSSLASNSSE
REDPMEKSDL KVVAPSVLNL YNEIERLDVE IDRLQKQRLI LKALLQKAEV INNVPELRIL
KKSLISLEKE LKFKSMQKEQ YIVQEGENSL YERSKVTIPS YITAKDKNGK SFIMYVIKVT
TLSRSDPNQI TANWMVTRRF SQFYELHNYL KSKYPLVSAM EFPKKKMVVK FIQGSLIEER
QKKLKGYLQA LVRNKDVCSD KIFRDFLSSE TFDATLDDTL QHVNEKIKKN TDGSGTKLYN
IISSQALYPL FSLANYKGLN DQMEDKLTPE KSTEPASSVS AESNTGKDDA FNMDDENITT
PESRAKDISF MKPICDLIVS IFQLNNSTSW FRGRALILLF QQLFGSTVEK VLRANIDGKI
KQEETVSKAL TGLQYTLWPD GEFKKKRKPR TDVEKERTKQ QTRMLLNAFL TDTSSKIFGQ
TAANRASDTL YFVFQNEILN RHLLLSLLDE CFSAIFPEIS R
//
