ID A0A1Q2YJQ5_9ASCO Unreviewed; 1986 AA.
AC A0A1Q2YJQ5;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 08-NOV-2023, entry version 24.
DE RecName: Full=RNA helicase {ECO:0008006|Google:ProtNLM};
GN ORFNames=PMKS-003257 {ECO:0000313|EMBL:GAV29755.1};
OS Pichia membranifaciens.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Pichiaceae; Pichia.
OX NCBI_TaxID=4926 {ECO:0000313|EMBL:GAV29755.1, ECO:0000313|Proteomes:UP000186136};
RN [1] {ECO:0000313|EMBL:GAV29755.1, ECO:0000313|Proteomes:UP000186136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KS47-1 {ECO:0000313|EMBL:GAV29755.1,
RC ECO:0000313|Proteomes:UP000186136};
RA Konishi M., Ishida M., Arakawa T., Kato Y., Horiuchi J.;
RT "Whole genome shotgun sequence of Pichia membranifaciens KS47-1.";
RL Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAV29755.1}.
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DR EMBL; BDGI01000135; GAV29755.1; -; Genomic_DNA.
DR Proteomes; UP000186136; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0010467; P:gene expression; IEA:UniProt.
DR GO; GO:0090304; P:nucleic acid metabolic process; IEA:UniProt.
DR CDD; cd18020; DEXHc_ASCC3_1; 1.
DR CDD; cd18795; SF2_C_Ski2; 2.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 2.60.40.150; C2 domain; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR Gene3D; 1.10.3380.10; Sec63 N-terminal domain-like domain; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004179; Sec63-dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR47961; DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED; 1.
DR PANTHER; PTHR47961:SF13; SEC63 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00270; DEAD; 2.
DR Pfam; PF00271; Helicase_C; 2.
DR Pfam; PF02889; Sec63; 2.
DR PIRSF; PIRSF039073; BRR2; 1.
DR SMART; SM00382; AAA; 2.
DR SMART; SM00487; DEXDc; 2.
DR SMART; SM00490; HELICc; 2.
DR SMART; SM00973; Sec63; 2.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 4.
DR SUPFAM; SSF158702; Sec63 N-terminal domain-like; 2.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 2.
DR PROSITE; PS51194; HELICASE_CTER; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000186136}.
FT DOMAIN 317..510
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 546..756
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 1176..1351
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 1388..1592
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 1986 AA; 226535 MW; 4E61E531E8310E5C CRC64;
MATYNVQSTG SYMQAMDPMR EKLSIIHIDN EEASLKLPTN LLKEESIASV RSDVHKNVHE
ILKAFESIDD DILADYEKIE ESDYDESDDS GDRDTFHYEA EDLTKLFLIN EIKEECNRVH
LKHTGGENVD SDSSQLFESI IDLLQKEDND AGLQGALFDI LGFEELDLIT KLITSKEEIL
RQYKRLNELK SNSARDSLNT NHQLMTVDQI KAKVAENARR AREQPLAKEH SVTKYPHVFM
AHNAGNIISF TGKAYTLPVG SVRESFEKHE EVIIPKSEKR NSSAPNIFIP IKELDFLCQG
TFKGYKTLNR MQSLIYDVGY NTNENMLVCA PTGAGKTDVA LLAILHTIKQ FVSESETSDT
ENLNVDIDYD EFKIVYVAPL KALAAEIVEK FSKKLAWLGI QVRELTGDMQ LTKAEIMTTQ
IIVTTPEKWD VVTRKSTGDS ELVQKVKLLI IDEVHLLHED RGSVIETLVA RTLRQVESTQ
SMIRIVGLSA TLPNFVDVAD FLGVNRNVGM FFFDQSFRPV PLEQQLVGVR GKAGSKQARE
NLEEVSFNKM IEMIKLDHQI MVFVHSRKDT AKTARNYMKM IGEQSYENYF DCRDSEKYAY
FEREMGKNRN KDLRELFVGG FGIHHAGMSR SDRNLTEKMF LAGAIKVLVC TATLAWGVNL
PAAAVIIKGT QVYDSKQGGF IDLGISDVIQ IFGRAGRPQF EAHGIGILCT SSDRLDHYIS
LLLQQHPIES KLAAKLVDNL NAEVSLGTVT NVEEGVQWLG YTYLYVRMKQ NPFAYGIDWQ
ELAQDPLLVQ RRRSMIIDAA RKLHKLQMIV FDERSLGLIP KDIGRISSDF YLLNESVEVF
NEMITSQASE ADVLSIISMS SEFDNVKFRD DEAKELDELK DERIVCEIGP KLESSQKKTN
ILLQSYISRA FVKDSALASD MSYIAQNAAR ICRSLFFMGL NRRWGIFTRH MLEICKAVDR
QMWPFQHPMN QFQLQPPIIK LIEAKKPTID HLRDMESGEL GDLVHNKSMG PKLHKLIGRF
PYLLLDVECF PITTNVMRIH VSIEPDFVWN FEYHGNAQFF WMLVEDSGNS NILHYEKFIL
NKKSFSSPHE MDFMIPLSDP PPPQILVRAI NDTWIGAENS VAVSFKHLIK PHNDTVKTEL
LKLHPLPVTA LHSKDVENIY RNKFSYFNPM QTMTFHTLYN TNSSVFVGSP TGSGKTVVAE
LAIWHAFNEF PGSKVVYIAP MKALVRERVD DWRARICQNT NHKIVELTGD SLPGVQEVRE
ADIIITTPEK FDGISRNWQS RKFVQQVSLL IMDEIHLLAS DRGPILEIIV SRMNYISSFT
KKPIRLLGLS TAVSNAMDMA SWLGVKEGLF NFPQSVRPVP LEMYIDGFPD NLAFCPLMKT
MNKPAFMAIK QHSPLKPVLI FVASRRQTRL TALDIIHLCG MEENPRRFLK IDEDELAPYI
NKVKDDTLKL ALQFGIGLHH AGLVEGDRQI SHKLFEQNKI QILIATSTLA WGVNLPAHLV
IIKGTQFFDA KIEGYKDMDL TDILQMMGRA GRPAFDTSGI AMVFTKESKK TFYKHFLNVG
FPVESSLHKV MDNHIGAEIS SGTIKTRQEA MDFLTWTFLY RRAHHNPTYY GIEDISQDGI
SSYLSGLIDK VINNLVESKC VITTGEKLES TPFLQISSYY YLSHKTIRNL LNKVIPYASF
RQCLRWLCEA TEYDELPTRH GEELINMEMS QEMRYSADDL EDYEFIWDPH IKAFLLLQAY
MTRIELPIAD YAQDTVSVLD QSLRILQAYI DATSEMRFLS TTLNFIKVMQ CIKQGCWFDD
DFVYALPGLK MKTSDHEKNF DLDGSEWKPT GENGQLTLKQ IASFKKRPNG MNKLAEKLRV
NKNKKDEFIR VASTLPTGEF KILEQNSAEE VGVELIHDNA MFRKDYRIYA PKFSKPQRET
WFVILCDLAE DELYAIKRES PRRAGGGVDK VQSKLKVAED LRGREVDILM VSDFTDLTYR
GRHKLK
//
