ID A0A1Q3AMQ6_CEPFO Unreviewed; 344 AA.
AC A0A1Q3AMQ6;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 28-JUN-2023, entry version 14.
DE RecName: Full=Probable magnesium transporter {ECO:0000256|RuleBase:RU363078};
GN ORFNames=CFOL_v3_00513 {ECO:0000313|EMBL:GAV56974.1};
OS Cephalotus follicularis (Albany pitcher plant).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Oxalidales; Cephalotaceae; Cephalotus.
OX NCBI_TaxID=3775 {ECO:0000313|EMBL:GAV56974.1, ECO:0000313|Proteomes:UP000187406};
RN [1] {ECO:0000313|Proteomes:UP000187406}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. St1 {ECO:0000313|Proteomes:UP000187406};
RA Fukushima K., Hasebe M., Fang X.;
RT "Cephalotus genome sequencing.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Acts as a Mg(2+) transporter. Can also transport other
CC divalent cations such as Fe(2+), Sr(2+), Ba(2+), Mn(2+) and Co(2+) but
CC to a much less extent than Mg(2+). {ECO:0000256|ARBA:ARBA00025284,
CC ECO:0000256|RuleBase:RU363078}.
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738,
CC ECO:0000256|RuleBase:RU363078}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363078};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU363078}. Early
CC endosome {ECO:0000256|RuleBase:RU363078}. Endosome
CC {ECO:0000256|ARBA:ARBA00004177}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the NIPA (TC 2.A.7) family.
CC {ECO:0000256|ARBA:ARBA00007001, ECO:0000256|RuleBase:RU363078}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAV56974.1}.
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DR EMBL; BDDD01000011; GAV56974.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Q3AMQ6; -.
DR InParanoid; A0A1Q3AMQ6; -.
DR OrthoDB; 926117at2759; -.
DR Proteomes; UP000187406; Unassembled WGS sequence.
DR GO; GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.3730.20; -; 1.
DR InterPro; IPR008521; Mg_trans_NIPA.
DR PANTHER; PTHR12570:SF65; MAGNESIUM TRANSPORTER NIPA9-RELATED; 1.
DR PANTHER; PTHR12570; UNCHARACTERIZED; 1.
DR Pfam; PF05653; Mg_trans_NIPA; 1.
DR SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 2.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|RuleBase:RU363078};
KW Endosome {ECO:0000256|RuleBase:RU363078};
KW Ion transport {ECO:0000256|RuleBase:RU363078};
KW Magnesium {ECO:0000256|RuleBase:RU363078};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363078};
KW Reference proteome {ECO:0000313|Proteomes:UP000187406};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU363078};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU363078}; Transport {ECO:0000256|RuleBase:RU363078}.
FT TRANSMEM 47..67
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363078"
FT TRANSMEM 73..93
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363078"
FT TRANSMEM 100..117
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363078"
FT TRANSMEM 129..150
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363078"
FT TRANSMEM 171..193
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363078"
FT TRANSMEM 199..220
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363078"
FT TRANSMEM 232..254
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363078"
FT TRANSMEM 266..284
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363078"
SQ SEQUENCE 344 AA; 37530 MW; 0073D391EF250AA0 CRC64;
MWESICFTLA ASAGNNIGKV LQKKGTVILP PLSFKLKVIR AYALNKAWVI GFLMDIFGAL
LMLRALSQAP VSVIQPVSGC GLAILSVFSH FYLKEVMNAI DWMGIALAGI GTIGVGAGGE
EQESSSISIF QLLWLALTVA ILFVLLNAWL RICKRQRREQ EMMEYEVVEE IIYGLESGIL
FGMASVISKM GFVFFEQHFY RMLFPLCISI SICCSGTGFY YQTRGLKHGR AIVISTCAAV
ASIVTGVLAG MLALGERLPS APGARLSLLL GWLLIVTGVI LLVSSSRLVQ HFRWPLPHFI
PSAVEKNFSP KRSASLRVKD PNPSAVIQAA TLHHLISSPT KEKA
//
