ID A0A1Q3CCX1_CEPFO Unreviewed; 276 AA.
AC A0A1Q3CCX1;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=poly(A)-specific ribonuclease {ECO:0000256|ARBA:ARBA00012161};
DE EC=3.1.13.4 {ECO:0000256|ARBA:ARBA00012161};
DE Flags: Fragment;
GN ORFNames=CFOL_v3_21557 {ECO:0000313|EMBL:GAV78089.1};
OS Cephalotus follicularis (Albany pitcher plant).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Oxalidales; Cephalotaceae; Cephalotus.
OX NCBI_TaxID=3775 {ECO:0000313|EMBL:GAV78089.1, ECO:0000313|Proteomes:UP000187406};
RN [1] {ECO:0000313|Proteomes:UP000187406}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. St1 {ECO:0000313|Proteomes:UP000187406};
RA Fukushima K., Hasebe M., Fang X.;
RT "Cephalotus genome sequencing.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Ubiquitous transcription factor required for a diverse set of
CC processes. It is a component of the CCR4 complex involved in the
CC control of gene expression. {ECO:0000256|ARBA:ARBA00025148}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Exonucleolytic cleavage of poly(A) to 5'-AMP.; EC=3.1.13.4;
CC Evidence={ECO:0000256|ARBA:ARBA00001663};
CC -!- COFACTOR:
CC Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240;
CC Evidence={ECO:0000256|ARBA:ARBA00001968};
CC -!- SUBUNIT: Component of the CCR4-NOT complex, at least composed of CRR4
CC and CAF1 proteins. {ECO:0000256|ARBA:ARBA00011757}.
CC -!- SIMILARITY: Belongs to the CAF1 family.
CC {ECO:0000256|ARBA:ARBA00008372}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAV78089.1}.
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DR EMBL; BDDD01001736; GAV78089.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Q3CCX1; -.
DR STRING; 3775.A0A1Q3CCX1; -.
DR InParanoid; A0A1Q3CCX1; -.
DR OrthoDB; 586746at2759; -.
DR Proteomes; UP000187406; Unassembled WGS sequence.
DR GO; GO:0030014; C:CCR4-NOT complex; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0004535; F:poly(A)-specific ribonuclease activity; IEA:UniProtKB-EC.
DR GO; GO:0006402; P:mRNA catabolic process; IEA:UniProt.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR039637; CNOT7/CNOT8/Pop2.
DR InterPro; IPR006941; RNase_CAF1.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR10797; CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT; 1.
DR PANTHER; PTHR10797:SF47; POLY(A)-SPECIFIC RIBONUCLEASE; 1.
DR Pfam; PF04857; CAF1; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE 3: Inferred from homology;
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Reference proteome {ECO:0000313|Proteomes:UP000187406};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:GAV78089.1"
SQ SEQUENCE 276 AA; 32102 MW; 84D48888BDFA5C6A CRC64;
NKSMTMTPQS KPVIVRQVWA DNLEFEISQI NEAILDYPFV AIDTEFPGTI FQLKPNMTYL
SHYPPFNYYM MKSNIDALNI IQLGLTLSDS EGRMPCFGTE FSVLWEFNFR DFDIDRDHQN
PESISLLQRQ GIDFKRNKKE GINSWDFAEL VASYGLVRNS SKLTWVTFHG SYDFGFLIKI
LTQRCLPCDI DSLMDLVADY FGFKVYDMKY MIQFSNGLHG GLERVAKSLY VERMVGKSHQ
AGSDSLLTMQ AFLRYTERYS KDYKNHNKKN FVLYGL
//
