ID A0A1Q3DVL9_LENED Unreviewed; 1246 AA.
AC A0A1Q3DVL9;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Rho guanine nucleotide exchange factor gef2 {ECO:0000313|EMBL:GAV98979.1};
GN ORFNames=LENED_000403 {ECO:0000313|EMBL:GAV98979.1};
OS Lentinula edodes (Shiitake mushroom) (Lentinus edodes).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Marasmiineae; Omphalotaceae; Lentinula.
OX NCBI_TaxID=5353 {ECO:0000313|EMBL:GAV98979.1, ECO:0000313|Proteomes:UP000188533};
RN [1] {ECO:0000313|EMBL:GAV98979.1, ECO:0000313|Proteomes:UP000188533}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 111202 {ECO:0000313|EMBL:GAV98979.1,
RC ECO:0000313|Proteomes:UP000188533};
RG Lentinula edodes genome sequencing consortium;
RA Sakamoto Y., Nakade K., Sato S., Yoshida Y., Miyazaki K., Natsume S.,
RA Konno N.;
RL Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:GAV98979.1, ECO:0000313|Proteomes:UP000188533}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 111202 {ECO:0000313|EMBL:GAV98979.1,
RC ECO:0000313|Proteomes:UP000188533};
RA Sakamoto Y., Nakade K., Sato S., Yoshida Y., Miyazaki K., Natsume S.,
RA Konno N.;
RT "A genome survey and senescence transcriptome analysis in Lentinula
RT edodes.";
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAV98979.1}.
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DR EMBL; BDGU01000007; GAV98979.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Q3DVL9; -.
DR STRING; 5353.A0A1Q3DVL9; -.
DR Proteomes; UP000188533; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR CDD; cd00160; RhoGEF; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR PANTHER; PTHR12673:SF270; DH DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR12673; FACIOGENITAL DYSPLASIA PROTEIN; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR PROSITE; PS50010; DH_2; 1.
PE 4: Predicted;
FT DOMAIN 98..295
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 642..874
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 907..976
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1036..1065
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1078..1111
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 643..700
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 701..715
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 717..739
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 778..801
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 817..834
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 851..872
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 931..976
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1097..1111
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1246 AA; 138389 MW; 9A2C7EE129832C32 CRC64;
MALASSPRKQ IPLATGDETR PRDLTPTVSP SHTKRVFFCG VVVEGSENGK ELTEEIKDLV
LSLGDVVEEE DVLGETNKEL GNIEHPATRK RALAESSALA SAINELVTTE RSYVKKLQTL
KRDYADPLRN FARSKSTAII SKYEATTLFG NIDSLLPVNE AFLTDLEKMI APNGYKAVGG
VGDVALRHFK ELKGFEQYRQ YYVKREEAQR FIEQEMEKRS SPFEDYIERV KYQSTDARNR
VGLRELLMEP VQRIPRYTLL FRLMIKHMPP HDPQRAKLEE ADDIASKIAL AEADEQTKRA
AIVYCLIATI DGFPPNMFSN SRRFIDCIDV EDILLEAPSS SSASSTSLVG SLHCTLFLFD
DKLLIVKRPG NGEKSGRVLA GLDELDKITK SGLPTGKKKN GMVCKGVLDV TDVVATDQGG
ADFHLYLETP PQDHSERWSG RPFRSLSVVH PPSPINLDPS QTEVDKQRFL KNLWNVQARY
RARSGQSVVL CSEEMEVESR GGRLTTARTY YNVYQRTAFL QEIKKTKIVV HVDALGTADD
IPFGMRGPPL AVIRLQPLAG GMCRYKVTSS DPSDPEEVDV VQTRRVPQRI VLTIHQFGLF
HFKTDKNSRP STPTARSKAS IFGLDAISRN LFNSRPGSSM GDFFAGSVSS RKRTKSTASR
SSTYTQTTST GESSITKFSS SRSNTMSTIA TTVDDGSLAS TRSRTKNDRG RSPGPSSDAD
DSFSRSLSRS LSRSISRASK SRSVSRDRES DYTDTDDDEQ IQILDRSDND IDAQLALARR
NSKSQNDRQV PVRSSQPSTA PIYEEEFPHP ARPASRASTA RDSTSQCTIT EDPRSPRSLS
RHSSDRRPMG PRSPSPLPPP RSPRPLSPPL PELPSIDDEL AAEISDIVQP TPTKSGIPRS
KRQIFHPVNN IDSTPKPHMN GMARASSSVE PLSIKKKTSV RNAIDSTDTP VTGRKSGRNS
LSRTPARTVT SSPRRVSPQI RLGKVAGPSV SSPHMVHDLD KIVSLARTTK EDVESSHRAV
KRLKVEVEKH TSAIVLSDND ISRPSSPAKG FRTPQRGAPP LTKAAQERLE EMRSLIGQRT
GESTPRSHRP PGGAPSTPLR QHSSVDSPSI FNTYNHATVG NHDAMQTALV KLSSAFKERT
NDLERSKVEL QNSRRQCEVV KSLLEESTKE KEIMYEAFNE ELDAMYNDVN LPEDEAWRAM
TEDLRVTKEA RNKLTQENCD LKQRLAEAEL RQEEWGALLR AHGLIP
//
