ID A0A1Q3E9D5_LENED Unreviewed; 1387 AA.
AC A0A1Q3E9D5;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=MFS general substrate transporter {ECO:0000313|EMBL:GAW03674.1};
GN ORFNames=LENED_005414 {ECO:0000313|EMBL:GAW03674.1};
OS Lentinula edodes (Shiitake mushroom) (Lentinus edodes).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Marasmiineae; Omphalotaceae; Lentinula.
OX NCBI_TaxID=5353 {ECO:0000313|EMBL:GAW03674.1, ECO:0000313|Proteomes:UP000188533};
RN [1] {ECO:0000313|EMBL:GAW03674.1, ECO:0000313|Proteomes:UP000188533}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 111202 {ECO:0000313|EMBL:GAW03674.1,
RC ECO:0000313|Proteomes:UP000188533};
RG Lentinula edodes genome sequencing consortium;
RA Sakamoto Y., Nakade K., Sato S., Yoshida Y., Miyazaki K., Natsume S.,
RA Konno N.;
RL Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:GAW03674.1, ECO:0000313|Proteomes:UP000188533}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 111202 {ECO:0000313|EMBL:GAW03674.1,
RC ECO:0000313|Proteomes:UP000188533};
RA Sakamoto Y., Nakade K., Sato S., Yoshida Y., Miyazaki K., Natsume S.,
RA Konno N.;
RT "A genome survey and senescence transcriptome analysis in Lentinula
RT edodes.";
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MYG1 family.
CC {ECO:0000256|ARBA:ARBA00010105}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAW03674.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BDGU01000150; GAW03674.1; -; Genomic_DNA.
DR STRING; 5353.A0A1Q3E9D5; -.
DR Proteomes; UP000188533; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd12577; RRM1_Hrp1p; 1.
DR Gene3D; 3.30.70.330; -; 2.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR034156; Hrp1_RRM1.
DR InterPro; IPR003226; Met-dep_prot_hydro.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR11215; METAL DEPENDENT HYDROLASE - RELATED; 1.
DR PANTHER; PTHR11215:SF1; MYG1 EXONUCLEASE; 1.
DR Pfam; PF07690; MFS_1; 1.
DR Pfam; PF00076; RRM_1; 2.
DR Pfam; PF03690; UPF0160; 1.
DR SMART; SM00360; RRM; 2.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 2.
DR PROSITE; PS50102; RRM; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 751..776
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 783..804
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 864..886
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 893..912
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 918..938
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 950..973
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 985..1005
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1063..1083
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1103..1121
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1133..1150
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1162..1180
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1355..1378
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 118..199
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 201..277
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 282..327
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1263..1306
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 303..327
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1278..1306
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1387 AA; 151511 MW; E427A02346EB14F5 CRC64;
MSDIDADLYG DLYETDFVDQ AADEKLTETP VQQPQVKTEV PATPKAPEAI QTASSNNHSV
PTTYAFSNVP TTVAPSVQQI PTYEEVSNDY TLSRLSGIQS ISSSEQRPVR PSEMKDDGKM
FIGGLHWDTT DDGLRTYFEQ FGKVEACTIM RDQAGRSRCF AFLTFEDPAS VNAVMVKEHV
LDGKIIDPKR AIPRQEHQRA TKLFIGGLAA TVTSESMREF FSQFGRVVDS TVMLDRETGR
SKGFGFVSLE DANVQPFLGF GNLEIDGKLI DVKLAQPRYQ REHFQEDEST GGNDGGFNNR
AGGGYANNFQ GGSGTAGGPF NAPATTGPSF DPQALAALYT RMFQMTSGGG MNMMPMMVMN
NMAGRGMGMA SGMGSMGMGR GAMLPEGAFR MASDAPVAKK ARTEKIIGTH NGTFHCDEAL
AVFLLRHTTA YQNSEVKRSR DPTVLDACDI VVDVGAVYDE SKQRFDHHQR GFEEVFGWGF
TTKLSSAGLV YKHFGKEIIS NQTQLPLDHP GVQTLWLKLY KELVESIDAN DNGISQYPTD
LKPRYRVRTD LSSRVAQLNP PWNKSLDAQG MDILFEKASS LTGSEFLGRL EYYANAWLPA
RDLLISAIQS SKSKVDSSGK IILLESFLPW KEHLFDLESE DASSTPPAAT YIVYPDEFSG
NWRVQAVPVS PESFESRKAL PEKWRGLRDD VFSETSGIQG GIFVHASGFI GGNKTKEGEG
SIGCPLTFKD TSILFYSLAG NANGTWPSPR YHALLIMFAF NASWTLLFST AYMLYLFDGA
THFLANVASS VIWVLLTSIL WGTAAGVMHN TRTGTDCPDV PPISRCRQSL TVEALGVGSH
YASYVLGPLK SRLSRELGAS HTEFSLLFSA YSLNSTWTPL IGGLLASTMG TTFTSILATG
IILAGQVLLL IGQVWGNIRM MAFGLFIFGL GVSPLAVVQE TIIVRFFKSH GLGVSMAFGL
IVGKGASFVS ARTSYPLTEH WGSHAPFYVA TFLAAMSFFV NLLYIMSSKW FVDGACAELE
AADISEEAKL RSRHNMSEAQ ALEKVARKKM VNLRDITKLG DVFWAYVGLN VLCGMIWSPF
THLSSNIIEK RYQMAEKNAA NTASYLLAGS IFLYPVCGFL VDRYKHRPII VQLMLVSSTL
TLLAFCWLVL PPDSTGTPIP AIASFAIGHG FSPLLLVVLV PKIVSLKYVS TALGVHKSLE
QTGSTIFQTL AGLALDNHVK DPAKGAPIGT EYAIQRLLNV FLALNVLHML TIVGLARLQR
KKDSEEEAEV EARRRLSGSA SVSVSPHPSV INRTSVNLGT GNDAGEEQPL LQATNANSHL
YGHPARNHSL SSGGSRIRQS MRNEKKLMRE RVRGGIFAGC SAALILFAWI LFMGTAYARL
GLGKKHL
//
