ID A0A1Q3GT74_9BACT Unreviewed; 1569 AA.
AC A0A1Q3GT74;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=Nephrocystin-3 {ECO:0000256|ARBA:ARBA00040387};
GN ORFNames=BKI52_20970 {ECO:0000313|EMBL:OJJ19288.1};
OS marine bacterium AO1-C.
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Cytophagaceae.
OX NCBI_TaxID=1905359 {ECO:0000313|EMBL:OJJ19288.1, ECO:0000313|Proteomes:UP000186474};
RN [1] {ECO:0000313|EMBL:OJJ19288.1, ECO:0000313|Proteomes:UP000186474}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AO1-C {ECO:0000313|EMBL:OJJ19288.1};
RA Buerger P., Wood-Charlson E.M., Weynberg K.D., Willis B., Van Oppen M.J.;
RT "CRISPR-Cas defence system in Roseofilum reptotaenium: evidence of a
RT bacteriophage-cyanobacterium arms race in the coral black band disease.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OJJ19288.1}.
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DR EMBL; MLAY01000007; OJJ19288.1; -; Genomic_DNA.
DR STRING; 1905359.BKI52_20970; -.
DR Proteomes; UP000186474; Unassembled WGS sequence.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.30.565.60; -; 2.
DR Gene3D; 3.40.50.1460; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011600; Pept_C14_caspase.
DR InterPro; IPR038475; RecG_C_sf.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR45641:SF1; NEPHROCYSTIN-3; 1.
DR PANTHER; PTHR45641; TETRATRICOPEPTIDE REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_6G03870); 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF00656; Peptidase_C14; 1.
DR Pfam; PF13424; TPR_12; 4.
DR SMART; SM00028; TPR; 9.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50005; TPR; 6.
DR PROSITE; PS50293; TPR_REGION; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000186474};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}; Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687}.
FT DOMAIN 2..216
FT /note="Peptidase C14 caspase"
FT /evidence="ECO:0000259|Pfam:PF00656"
FT DOMAIN 786..956
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
FT REPEAT 1220..1253
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 1262..1295
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 1304..1337
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 1346..1379
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 1430..1463
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 1472..1505
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ SEQUENCE 1569 AA; 179568 MW; 6FDC9B8FF447FA42 CRC64;
MANDLEAGKN DVLKIFEILT DRDIVGCDKT NSKKIIDCAS VNEFKKTLEE VLSTWDSSSQ
LVFYFSGHGV IKSEKFFLKF GMGESLFNNL FDFTHLIEFF KDCKVGKAII IIDACHSGKA
AKNIKSSNLK PIKTSLPSSE EIPTGISILA SSRANQFSEE LEDGSHSVFT KLLHECLKNG
LGDNFNHEQD ITPGLISDYV NIRLKNTEYE QQPIVSIGGA SGKIILARNR SYIGDSVITD
TVSNESQLRI LYENTAGSEH PCVGATVDGL DAELLEEYFF NTGIDLRINP LSLKELLEKH
HFYSKITLKG IQKSLHKAAV LCFHLSPQDF YRGAFVKLEF DETNKESNDF KGNLVNQSIE
VFEEIKNYLL EIKIRDQLII NLMREVVTNA IIHRNYDVNI HTTIKINPQR LIIINPGIFE
YFNDWRQFLE HEISAPANPA ITQYISKLMR YEGVGRGFRI IKDYLKKYGK DSIEFTTIEQ
KATKLVVRFY TIDDAVKEAE LQHKHIIDDN EVSSDAKLLS LRTRNGIEPC FEANIESLDW
NLLERFFNSK GEELPKENRN YLLEKYGMLH SFKTNQAVLN KSTVLSFHNN PQLFYPSTKI
VFTAGDLTSE HYIKNDIVGN LFMQVSSLTQ KIIQFLPRRH MIDENGNRFE SSIIDEALVK
DTIFNTIIQR DYSVDIPTQV RVEENVLVII NPGKELQSAW DEKNLLFNNT PKNPLISYFL
NLSVGEDEDF SVYQNYLEEN GKDSLKVEVI DGKLTKVIIK FSRNIPKYLT SYVPSINPKD
VIGRTHKLEE LVKSLDSSKK AVVVAGIGGI GKSTLAKLYL AKYRDSLDHI IWLTFNTESF
EEMILKSTVP EKLDISRKQI SNEILLKLVF NKLSSLNGNN LLVIDNADNV PEIKKYSSLL
SLGNSWKVLL TSRSVLPNME LIRVDKLSSR SARDLFLKHY SVNAEDEKVL EALLREVDYH
TLTVELLAKT IQKSWSLGLE DLLSKMKMPQ LDDPNLREHI WTSNHLSEEE EILAVYSHIS
ACFDLASLNI KEQWMLQQFA VLPSLATIDG RVLTQWLTYE KNAEEKHKLQ SLIENLVDKG
WLIISRQNKL LFQIHPIIKS LILFRLTPHF ENCKFLIKGF SNFIRIDATT QDITGKFMWV
EFGEELIKIF GINNNKSTLE EVHTISILYD ELGYVYQQQG NFVRSLALKN TALELVQNWY
NIYEKDLTQS KNRELENLIV SYKSNLSLVY QDLGEYEEAR KLLEDALEVN IRNFNEFSPK
VTILQSNLGL IYRELGKYET AKSLLEQALK NDLKNFGESH PEVAIRQSNL GLIYQDLGQY
KKAEELFNNS LKISIKNFGE SHPEVAIRQS NLGLVYRELG EYNKALELLE KALKNDWKNF
GTSHPTVLIR QSNLSLIYRD LKAFDEALDL LQNSLETSER IFEESHPTIT SIQSNLSMLY
RELGEFEKAR ELLEKALNSQ VKNFGTSHPA VAISQSNLGL VLKELGELEK ARSLFEKALE
NDLKNFEASH PTVAISQHNL ATTYLNLGMK QEARQLFQKA YISLYNLLGE EHPNTKTVKN
QLDKLDFNY
//
