ID   A0A1Q3H388_9BACT        Unreviewed;       858 AA.
AC   A0A1Q3H388;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Polynucleotide kinase-phosphatase {ECO:0000313|EMBL:OJJ23337.1};
GN   ORFNames=BKI52_02970 {ECO:0000313|EMBL:OJJ23337.1};
OS   marine bacterium AO1-C.
OC   Bacteria; Bacteroidota; Cytophagia; Cytophagales; Cytophagaceae.
OX   NCBI_TaxID=1905359 {ECO:0000313|EMBL:OJJ23337.1, ECO:0000313|Proteomes:UP000186474};
RN   [1] {ECO:0000313|EMBL:OJJ23337.1, ECO:0000313|Proteomes:UP000186474}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AO1-C {ECO:0000313|EMBL:OJJ23337.1};
RA   Buerger P., Wood-Charlson E.M., Weynberg K.D., Willis B., Van Oppen M.J.;
RT   "CRISPR-Cas defence system in Roseofilum reptotaenium: evidence of a
RT   bacteriophage-cyanobacterium arms race in the coral black band disease.";
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OJJ23337.1}.
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DR   EMBL; MLAY01000001; OJJ23337.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Q3H388; -.
DR   STRING; 1905359.BKI52_02970; -.
DR   Proteomes; UP000186474; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd07423; MPP_Prp_like; 1.
DR   Gene3D; 3.60.21.10; -; 1.
DR   Gene3D; 3.30.470.30; DNA ligase/mRNA capping enzyme; 2.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR   InterPro; IPR029052; Metallo-depent_PP-like.
DR   InterPro; IPR041780; MPP_PrpE-like.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR024028; PNKP_bac.
DR   InterPro; IPR032380; PNKP_ligase_dom.
DR   InterPro; IPR006186; Ser/Thr-sp_prot-phosphatase.
DR   NCBIfam; TIGR04075; bacter_Pnkp; 1.
DR   PANTHER; PTHR42850:SF7; BIS(5'-NUCLEOSYL)-TETRAPHOSPHATASE PRPE [ASYMMETRICAL]; 1.
DR   PANTHER; PTHR42850; METALLOPHOSPHOESTERASE; 1.
DR   Pfam; PF13671; AAA_33; 1.
DR   Pfam; PF00149; Metallophos; 1.
DR   Pfam; PF16542; PNKP_ligase; 1.
DR   PRINTS; PR00114; STPHPHTASE.
DR   SUPFAM; SSF56091; DNA ligase/mRNA capping enzyme, catalytic domain; 1.
DR   SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Kinase {ECO:0000313|EMBL:OJJ23337.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000186474};
KW   Transferase {ECO:0000313|EMBL:OJJ23337.1}.
FT   DOMAIN          182..383
FT                   /note="Calcineurin-like phosphoesterase"
FT                   /evidence="ECO:0000259|Pfam:PF00149"
FT   DOMAIN          474..852
FT                   /note="Polynucleotide kinase-phosphatase ligase"
FT                   /evidence="ECO:0000259|Pfam:PF16542"
SQ   SEQUENCE   858 AA;  97169 MW;  A97A4790366D61AB CRC64;
     MEISVPELSL VLLVGVSGSG KSTFARQHFT KYEIVSSDEC RALVSNDENS KDATNDAFDL
     LYYIVGKRLK RGLLTVVDAT NVQVASRKGL IALAREYHVL PTVIVLDMPQ RVCEERNEQR
     VDRNFGDHVI RQQHQQLKKS IKGLKREGFR KIYTLRSPEE VANVSGITRE KLYNDKKHIT
     GPFDIIGDIH GCYDETLALL EKLGYQLNSV EDDGQNFGLE VTHPENRQVI FLGDLVDRGP
     NSPAVLRLVM SMVRSGVAWC VPGNHDLKLH KKLKGKNVAI NHGLVETLEQ LVDEPPAFID
     AVKEFLYDLV SHYVFDEGKL VVSHAGIKEE MQGRGSAAVR AFCLYGETTG EIDEFGLPVR
     YNWASEYRGR AKVVYGHTPV PEAEWLNKTI DIDTGCVFGG KLTALRYPEE TLVSVPAQKV
     YSEPVKPLQP ESEEVLSHQQ VYDNLLNIED VTGKRIVQTR LRNNITIQEE NSIAALEVMS
     RFAINPKWLI YLPPTMSPCA TSELPGFLEH PQQAINYYKS RGIEKIVCEE KHMGSRVVLV
     VCKDETVAQT RFGIVNEGIG VAYTRTGRSF FTNQDLEQQF LQRINDALTQ SNFWAKHQTD
     WVCLDTELMP WSAKAQALLQ SQYASVGTAA ENALGEVNQV LQQALKRGIG DAKSSLEKFT
     YKQSAIAKYR QAYRNYCWEV NSVEDYKLAP FHILATEGAV HTDKNHEWHM ENIREICEAD
     SQMFRMTPYK IVETKNETSV QTAIDWWLEL TGKGGEGMVV KPYDFIVYGS KDGLLQPAVK
     CRGSEYLRII YGPEYDMPEN IKRLKNRALG RKRSLALREF ALGIEGLERF VRKEPLRRIH
     ESVFGVLALE SEEMDPRL
//