ID A0A1Q3RRG2_9FIRM Unreviewed; 946 AA.
AC A0A1Q3RRG2;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=Diguanylate cyclase {ECO:0008006|Google:ProtNLM};
GN ORFNames=BGO41_04495 {ECO:0000313|EMBL:OJV66687.1};
OS Clostridiales bacterium 38-18.
OC Bacteria; Bacillota; Clostridia; Eubacteriales.
OX NCBI_TaxID=1895746 {ECO:0000313|EMBL:OJV66687.1, ECO:0000313|Proteomes:UP000185881};
RN [1] {ECO:0000313|EMBL:OJV66687.1, ECO:0000313|Proteomes:UP000185881}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=38-18 {ECO:0000313|EMBL:OJV66687.1};
RA Kantor R.S., Huddy R.J., Iyer R., Thomas B.C., Brown C.T., Anantharaman K.,
RA Tringe S., Hettich R.L., Harrison S.T., Banfield J.F.;
RT "Genome-resolved meta-omics ties microbial dynamics to process performance
RT in biotechnology for thiocyanate degradation.";
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OJV66687.1}.
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DR EMBL; MKTL01000001; OJV66687.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Q3RRG2; -.
DR STRING; 1895746.BGO41_04495; -.
DR Proteomes; UP000185881; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd06225; HAMP; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR PANTHER; PTHR33121:SF71; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF00672; HAMP; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00304; HAMP; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 429..446
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 448..500
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 552..684
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 693..946
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
FT COILED 492..519
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 946 AA; 107985 MW; 60BDA337F0434EA6 CRC64;
MKKIFSQYRS SLNYKITLST ILIVIIGIVS IILYTQISVK RLSDQTLDKM SGELDALIVD
FYGEHIIEVA SNLQAEYDKY FDELSIFGHI AQNYFDNYEA MSPGVEQLLE APIFNDHLTN
NGNWLQNQDD EPTTVFLGRY LLDEKGNIPL SVSELIKKTS FFDLFMPAFA SNGAEKLQIY
FTGGEQLDFT RMAPWVNIGE GIYDVYPELY DLPMWQTFNP GLIKDWTDFK NRVGVGNEKL
IRTGKPVQDG ITGEVNIGMT YPIFSPTDGS FLGELAYDIP LSYFIDYTES LRLGKNGFAV
LMQSNGNVFA INNLGKSVLG FEESGDGLKI TEEGFNTLER NIKDSKYEDV QNIDFKSFDE
LKEVSINGAA YFIVSTRTNE YTTWQSDKGF TEDHWTMALI LPKEEVYSLY FNFEDQVNHI
ANIALKDQLY IAIIITFFVL AFIMLYNSKL TRKLNLLTHA VKELRYNQFS EPIEIDSNDE
IGKLSTAFNE MQTEIHQTIE KLNVQNERLK DEIAERIKKD RIIDYLENFD AHTDLLNKKA
LFNILKEMKD SPTVSLITIG IDELRKINDA YTYKVGDDII IETVRRLSDM VEDKELLFRT
GGDEFTIILK GLSAEALILK CDEIISVFKK PFVTIMHEIS VSCSVGVSTY PNDTQEPMDL
FKFSNVALNH AKEGNKGGYS FYSSQMNEKV RTRMETINEL NHAIERNEFS LHYQPIIDLK
TGKVVALEAL IRWQSEKLGN IPPAIFIALA EETKQIVKIG DWVVSNALQH LKILERDGHD
RLNMAINISV VQFYQPGFIE RIKQLIGQYE INPKRLTFEV TEGVFLNDLN KAQSVIEELK
GLGIHIAVDD FGTGYSSLAY LRNLKVNHLK IDRTFISESL DQTSQEIINA ILALANSLKL
TVVAEGIETY DQKEYLIEKG CQFGQGYLFS KPQPFDLLLD WLEDEK
//
