ID A0A1Q3S7K3_9FLAO Unreviewed; 225 AA.
AC A0A1Q3S7K3;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 12.
DE RecName: Full=D-lactate dehydratase {ECO:0000256|ARBA:ARBA00013134};
DE EC=4.2.1.130 {ECO:0000256|ARBA:ARBA00013134};
GN ORFNames=BGO42_03505 {ECO:0000313|EMBL:OJV72319.1};
OS Flavobacterium sp. 40-81.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Flavobacterium.
OX NCBI_TaxID=1896169 {ECO:0000313|EMBL:OJV72319.1, ECO:0000313|Proteomes:UP000185767};
RN [1] {ECO:0000313|EMBL:OJV72319.1, ECO:0000313|Proteomes:UP000185767}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=40-81 {ECO:0000313|EMBL:OJV72319.1};
RA Kantor R.S., Huddy R.J., Iyer R., Thomas B.C., Brown C.T., Anantharaman K.,
RA Tringe S., Hettich R.L., Harrison S.T., Banfield J.F.;
RT "Genome-resolved meta-omics ties microbial dynamics to process performance
RT in biotechnology for thiocyanate degradation.";
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + methylglyoxal = (R)-lactate + H(+);
CC Xref=Rhea:RHEA:27754, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:16004, ChEBI:CHEBI:17158; EC=4.2.1.130;
CC Evidence={ECO:0000256|ARBA:ARBA00001524};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OJV72319.1}.
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DR EMBL; MKTM01000012; OJV72319.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Q3S7K3; -.
DR STRING; 1896169.BGO42_03505; -.
DR Proteomes; UP000185767; Unassembled WGS sequence.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.
DR CDD; cd03141; GATase1_Hsp31_like; 1.
DR Gene3D; 3.40.50.880; -; 1.
DR InterPro; IPR029062; Class_I_gatase-like.
DR InterPro; IPR002818; DJ-1/PfpI.
DR PANTHER; PTHR48094:SF11; GLUTATHIONE-INDEPENDENT GLYOXALASE HSP31-RELATED; 1.
DR PANTHER; PTHR48094; PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED; 1.
DR Pfam; PF01965; DJ-1_PfpI; 1.
DR SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
PE 4: Predicted;
KW Glutamine amidotransferase {ECO:0000313|EMBL:OJV72319.1};
KW Stress response {ECO:0000256|ARBA:ARBA00023016};
KW Transferase {ECO:0000313|EMBL:OJV72319.1}.
FT DOMAIN 27..220
FT /note="DJ-1/PfpI"
FT /evidence="ECO:0000259|Pfam:PF01965"
SQ SEQUENCE 225 AA; 24629 MW; B149E13D76F2C0DE CRC64;
MKKKILFVVT SHGQKGSTGE PTGYYLSEVS HPWEVLHNAG YEIDFVSPKG GKAPVDGFDL
KDPINKKFWD DKTYHAKVEN TMKPSEVNPK DYVAIHFAGG HGAMWDLPEN KEIAALAAKI
YENNGIVSAV CHGPAGLVNI KLTNGKYLVD GKKVNGFTNE EEIAVGLEKV VPFMLEDKLI
ERGAEFEKTG LWQSHAVADQ RLVTGQNPAS AEAVGKKVLA ELQKL
//
