ID   A0A1Q4DLM4_9PSEU        Unreviewed;       650 AA.
AC   A0A1Q4DLM4;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Acetoacetate--CoA ligase {ECO:0000313|EMBL:OJY45243.1};
GN   ORFNames=BGP03_15750 {ECO:0000313|EMBL:OJY45243.1};
OS   Pseudonocardia sp. 73-21.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Pseudonocardia.
OX   NCBI_TaxID=1895809 {ECO:0000313|EMBL:OJY45243.1, ECO:0000313|Proteomes:UP000186163};
RN   [1] {ECO:0000313|EMBL:OJY45243.1, ECO:0000313|Proteomes:UP000186163}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=73-21 {ECO:0000313|EMBL:OJY45243.1};
RA   Kantor R.S., Huddy R.J., Iyer R., Thomas B.C., Brown C.T., Anantharaman K.,
RA   Tringe S., Hettich R.L., Harrison S.T., Banfield J.F.;
RT   "Genome-resolved meta-omics ties microbial dynamics to process performance
RT   in biotechnology for thiocyanate degradation.";
RL   Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OJY45243.1}.
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DR   EMBL; MKVV01000057; OJY45243.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Q4DLM4; -.
DR   STRING; 1895809.BGP03_15750; -.
DR   Proteomes; UP000186163; Unassembled WGS sequence.
DR   GO; GO:0030729; F:acetoacetate-CoA ligase activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   InterPro; IPR005914; Acac_CoA_synth.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   NCBIfam; TIGR01217; ac_ac_CoA_syn; 1.
DR   PANTHER; PTHR42921; ACETOACETYL-COA SYNTHETASE; 1.
DR   PANTHER; PTHR42921:SF1; ACETOACETYL-COA SYNTHETASE; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF13193; AMP-binding_C; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:OJY45243.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   DOMAIN          89..463
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
FT   DOMAIN          531..605
FT                   /note="AMP-binding enzyme C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13193"
SQ   SEQUENCE   650 AA;  70693 MW;  26D1A916C50C28A3 CRC64;
     MDAVWTPTAD RIEHSALRDY LNWLEKREGC SFPDHDALHA WSVEDLDRFW VSLVDYYQVE
     FSTPWRHVRT SDPMPRTRWF PGARLNFAQH ALRHGDDDAV ALVCVQEGGL PAREITWAAL
     RRSVAAVAGW LREAGVQPGD RVGAYLPNTE HAVIGCLAAA AVGAVWACCS PDFGADGTTG
     RLAQLEPTVL IAADGYHWNG KEIDRGDVVA QLRENLPTVR HVVHVAVLDR PAPDGATPWD
     ELLATDAAPE FEQVEFSHPL WVLFTSGTTG LPKGLVHGHG GITLQGLEWA GLYGGLRTGE
     RMFTYTSTGW ALWNIQLDAL TQGASIVLYE GSPNHPAGAI WEVAARTGAD LMLLGAAVVM
     ATANTGVSPR QEHDLSRLRH VSVSGSALPP AGYEWLLEHV GDLRIDSTSG GTDISGSFVG
     ANEYAPVQAG RIGGKIAGVD CAAWDEDGNP VVDEVGDLVI TQPMPSMPVQ LWNDPDAVRY
     TESYFDTWPG VWRHGDWVTM HSDGSISIHG RSDSTLNRQG VRLGSSDFYD VLETLPEITE
     TLVIGVDLPD DSYWLGLFVV PAAGHEVDDT LKQKIVSTLR TRLTPRHVPD EILAAPAVPH
     TLSGKKLEVP IKKLLAGRPL EKAANMASVD DPDALRWYAR FAEDRAGSAT
//