ID   A0A1Q4H4R9_9MYCO        Unreviewed;       349 AA.
AC   A0A1Q4H4R9;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Polyprenyl synthetase {ECO:0000313|EMBL:OJZ62536.1};
GN   ORFNames=BRW64_26675 {ECO:0000313|EMBL:OJZ62536.1};
OS   Mycolicibacterium diernhoferi.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC   Mycolicibacterium.
OX   NCBI_TaxID=1801 {ECO:0000313|EMBL:OJZ62536.1, ECO:0000313|Proteomes:UP000186837};
RN   [1] {ECO:0000313|EMBL:OJZ62536.1, ECO:0000313|Proteomes:UP000186837}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bard {ECO:0000313|EMBL:OJZ62536.1,
RC   ECO:0000313|Proteomes:UP000186837};
RA   Greninger A.L., Fang F., Jerome K.R.;
RT   "Genome sequences of unsequenced Mycobacteria.";
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- PATHWAY: Isoprenoid biosynthesis. {ECO:0000256|ARBA:ARBA00005128}.
CC   -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC       {ECO:0000256|ARBA:ARBA00006706, ECO:0000256|RuleBase:RU004466}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OJZ62536.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; MPNS01000025; OJZ62536.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Q4H4R9; -.
DR   STRING; 1801.BRW64_26675; -.
DR   Proteomes; UP000186837; Unassembled WGS sequence.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR   CDD; cd00685; Trans_IPPS_HT; 1.
DR   Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR   InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR   InterPro; IPR000092; Polyprenyl_synt.
DR   InterPro; IPR033749; Polyprenyl_synt_CS.
DR   PANTHER; PTHR12001:SF88; (2E,6E)-FARNESYL DIPHOSPHATE SYNTHASE; 1.
DR   PANTHER; PTHR12001; GERANYLGERANYL PYROPHOSPHATE SYNTHASE; 1.
DR   Pfam; PF00348; polyprenyl_synt; 1.
DR   SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR   SUPFAM; SSF48576; Terpenoid synthases; 1.
DR   PROSITE; PS00723; POLYPRENYL_SYNTHASE_1; 1.
DR   PROSITE; PS00444; POLYPRENYL_SYNTHASE_2; 1.
PE   3: Inferred from homology;
KW   Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW   Lipid metabolism {ECO:0000256|ARBA:ARBA00022516};
KW   Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW   Transferase {ECO:0000256|RuleBase:RU004466}.
SQ   SEQUENCE   349 AA;  38161 MW;  D26F01ACC3A0B93C CRC64;
     MAPLRRSVLG AVTEFLDVNC REALYGAHVD IAELVLRGML AEGKCLRSTY LYLGWQCGAR
     PDAAALRAAA SLELLHAFAL LQDDVMDESS MRRGRPSAHR AFERWHRERG LPGSSARFGE
     SAAVLLGDLC LVWAEQMLRE SGLEEAALAR AWPRYDAMRT ELAIGQFADL VNDSAGFPDF
     DDVLDVARRK SGNYTVRRPL EIGAALAGCD DEVIAVLGRY GEAIGEAFQL RDDLLGVFGA
     PRTTGKPTGT DLVARKATTV VVAGYRLAGG AQQRQFKEFM TAQQLSSDDV TRWQALISEV
     GTVQRIEDMI HRRFAAAVQA LDSLDEARLR PDARSALITM ASACTERVS
//