ID A0A1Q4H7K6_9MYCO Unreviewed; 414 AA.
AC A0A1Q4H7K6;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=MBL fold metallo-hydrolase {ECO:0000313|EMBL:OJZ63422.1};
GN ORFNames=BRW64_22725 {ECO:0000313|EMBL:OJZ63422.1}, BV510_07450
GN {ECO:0000313|EMBL:OPE54977.1}, CRI78_12955
GN {ECO:0000313|EMBL:PEG53998.1};
OS Mycolicibacterium diernhoferi.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=1801 {ECO:0000313|EMBL:OJZ63422.1, ECO:0000313|Proteomes:UP000186837};
RN [1] {ECO:0000313|EMBL:OPE54977.1, ECO:0000313|Proteomes:UP000191039}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BM1 {ECO:0000313|EMBL:OPE54977.1,
RC ECO:0000313|Proteomes:UP000191039};
RA Greninger A.L., Jerome K.R., Mcnair B., Wallis C., Fang F.;
RT "genome sequences of unsequenced Mycobacteria.";
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:OJZ63422.1, ECO:0000313|Proteomes:UP000186837}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bard {ECO:0000313|EMBL:OJZ63422.1,
RC ECO:0000313|Proteomes:UP000186837};
RA Greninger A.L., Fang F., Jerome K.R.;
RT "Genome sequences of unsequenced Mycobacteria.";
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:PEG53998.1, ECO:0000313|Proteomes:UP000220340}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IP141170001 {ECO:0000313|EMBL:PEG53998.1,
RC ECO:0000313|Proteomes:UP000220340};
RA Tortoli E., Trovato A., Cirillo D.M.;
RT "The new phylogeny of genus Mycobacterium.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OJZ63422.1}.
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DR EMBL; MPNS01000016; OJZ63422.1; -; Genomic_DNA.
DR EMBL; MIJD01000053; OPE54977.1; -; Genomic_DNA.
DR EMBL; PDCR01000015; PEG53998.1; -; Genomic_DNA.
DR RefSeq; WP_073858718.1; NZ_PDCR01000015.1.
DR AlphaFoldDB; A0A1Q4H7K6; -.
DR STRING; 1801.BRW64_22725; -.
DR OrthoDB; 5240502at2; -.
DR Proteomes; UP000186837; Unassembled WGS sequence.
DR Proteomes; UP000191039; Unassembled WGS sequence.
DR Proteomes; UP000220340; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR Gene3D; 1.25.40.880; Alkyl sulfatase, dimerisation domain; 1.
DR Gene3D; 3.60.15.30; Metallo-beta-lactamase domain; 1.
DR InterPro; IPR038536; Alkyl/aryl-sulf_dimr_sf.
DR InterPro; IPR029228; Alkyl_sulf_dimr.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR PANTHER; PTHR43223; ALKYL/ARYL-SULFATASE; 1.
DR PANTHER; PTHR43223:SF2; LACTAMASE_B DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF14863; Alkyl_sulf_dimr; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:OJZ63422.1}.
FT DOMAIN 37..245
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 414 AA; 45525 MW; 8A74750D7362A6A5 CRC64;
MSTYEPVYLG RPGADDIVGA GAPAEEVSPG IWLSPGLSNS FMLTTDAGRI VLNTGMGFEG
PVHRANFDAV DAAPIRYIIL TQGHVDHVGG IDSIADPGTD IVAQTSWETW RRDNELLAEF
RARNSAFAWI DKVMATIERT TARFGSVPAQ SVPIPTVTFD DELVIELGGR RLELYATPGG
ETTDSLVVWL PDEGVCLCGN VFGALFGHIP NLVTMRGDRY RDALTVVESI DRVRALGAET
LLTGHFGPIV GKDRIEWELT RLRDAVSYIH DRTVEGMNAG KDVHTLMREV VLPADLEVGQ
GYGMVRWNVR AIWENYAGWF HHRSTAELYA EHPDRTEADL LELAGTATVL HRARTLLDAG
EPVRALRLAE IVNQTDPANK EATDVLIAAH ELLLESSTNF WETAWLHQQI AKLA
//
