ID A0A1Q4V6Q3_9ACTN Unreviewed; 302 AA.
AC A0A1Q4V6Q3;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Beta-lactamase {ECO:0000313|EMBL:OKH93528.1};
GN ORFNames=AB852_18885 {ECO:0000313|EMBL:OKH93528.1};
OS Streptomyces uncialis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1048205 {ECO:0000313|EMBL:OKH93528.1, ECO:0000313|Proteomes:UP000186455};
RN [1] {ECO:0000313|EMBL:OKH93528.1, ECO:0000313|Proteomes:UP000186455}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DCA2648 {ECO:0000313|EMBL:OKH93528.1,
RC ECO:0000313|Proteomes:UP000186455};
RA Yan X., Huang T., Ge H., Shen B.;
RT "Cloning and characterization of the uncialamcin biosynthetic gene
RT cluster.";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKH93528.1}.
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DR EMBL; LFBV01000004; OKH93528.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Q4V6Q3; -.
DR STRING; 1048205.AB852_18885; -.
DR Proteomes; UP000186455; Unassembled WGS sequence.
DR GO; GO:0008800; F:beta-lactamase activity; IEA:InterPro.
DR GO; GO:0030655; P:beta-lactam antibiotic catabolic process; IEA:InterPro.
DR GO; GO:0046677; P:response to antibiotic; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR045155; Beta-lactam_cat.
DR InterPro; IPR000871; Beta-lactam_class-A.
DR PANTHER; PTHR35333; BETA-LACTAMASE; 1.
DR PANTHER; PTHR35333:SF4; SLR0121 PROTEIN; 1.
DR Pfam; PF13354; Beta-lactamase2; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000186455}.
FT DOMAIN 26..272
FT /note="Beta-lactamase class A catalytic"
FT /evidence="ECO:0000259|Pfam:PF13354"
FT REGION 68..87
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 302 AA; 31902 MW; 49CA5C93419AFD3B CRC64;
MMTGTEGLLA DMRRQLRDGG LRGCLLVRDL RSGEEVGIEP DVALPAASLV KVPLALATAE
RVRRGELDGA TALDVPPGRI TTPGPTGLSR FRHPARIAID DLLYLSTCVS DGSAADALFG
LTPPARVTAL LQECGVDGIT VRHSVSELSD TPVERFDADG AHLAHALAID SGTGGRGHRV
PQLDTTRAST GTARSWVGLL QALWTPSPVH PEVAGRVRGL MAHNVLRHRL APDFDSDAAT
WSSKTGTLLN LRHEIGVVEH ADGQAFAVAA LTESLVPAAT QPGADALMAH VARTLRDHLR
QL
//
