ID A0A1Q4V9H6_9ACTN Unreviewed; 534 AA.
AC A0A1Q4V9H6;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE RecName: Full=VWFA domain-containing protein {ECO:0000259|SMART:SM00327};
GN ORFNames=AB852_08855 {ECO:0000313|EMBL:OKH94409.1};
OS Streptomyces uncialis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1048205 {ECO:0000313|EMBL:OKH94409.1, ECO:0000313|Proteomes:UP000186455};
RN [1] {ECO:0000313|EMBL:OKH94409.1, ECO:0000313|Proteomes:UP000186455}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DCA2648 {ECO:0000313|EMBL:OKH94409.1,
RC ECO:0000313|Proteomes:UP000186455};
RA Yan X., Huang T., Ge H., Shen B.;
RT "Cloning and characterization of the uncialamcin biosynthetic gene
RT cluster.";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKH94409.1}.
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DR EMBL; LFBV01000002; OKH94409.1; -; Genomic_DNA.
DR RefSeq; WP_073785873.1; NZ_LFBV01000002.1.
DR AlphaFoldDB; A0A1Q4V9H6; -.
DR STRING; 1048205.AB852_08855; -.
DR Proteomes; UP000186455; Unassembled WGS sequence.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR36846; PROTEIN VIAA; 1.
DR PANTHER; PTHR36846:SF1; PROTEIN VIAA; 1.
DR Pfam; PF13519; VWA_2; 1.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000186455}.
FT DOMAIN 351..534
FT /note="VWFA"
FT /evidence="ECO:0000259|SMART:SM00327"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 136..163
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..28
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 534 AA; 57359 MW; 0785688A0BAF301B CRC64;
MGRTPSRHNE SSSRAGGKLS TSATAPERHR TTVVVDRFDQ ISWRDTYEQS AGLSELAKEL
NERYGCGADL LADAFQAAYK VSARLRERAE MDRSRLVNHQ IITALAESCE FAELRRVTVG
DPYAAAMAVL AQAPALRRML EHSRNAQEQA EQVEKAQQNA ASDATTLCEA LRRTAGSADE
DTAVSASDAV QHSIKAATAA ARQSDRSAAQ ALPAAAPGMG ATARSAAMKA VEIVRGEAAL
MRAWGIGPGE LEKMPFDQRA QLAERLRTGR LAQWAELIGR FRQMASGERA RKVANATGEL
VGVTLGDDLS RVIPSELVNL GLPELRAVFA ARYAAGELML YHSQGEQATG QGAIIACVDT
SHSMYLAGRD GVSREAWAKA CALALLDQAR HAKRDFVGIL FSAADKIQVF RFPAGQPADP
AQVLDFAETF LGGGTSYQTP LTAAGELLAE ELNDAARGRG DIVMITDDEC GIAEEWMRGW
NIAKHRLGFR VFGVAIGAPR ATEADSVLDA LCDNLRSIED LTDVSAAADL FRMI
//
