ID A0A1Q4VBJ2_9ACTN Unreviewed; 905 AA.
AC A0A1Q4VBJ2;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=alpha-L-rhamnosidase {ECO:0000256|ARBA:ARBA00012652};
DE EC=3.2.1.40 {ECO:0000256|ARBA:ARBA00012652};
GN ORFNames=AB852_10350 {ECO:0000313|EMBL:OKH95218.1};
OS Streptomyces uncialis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1048205 {ECO:0000313|EMBL:OKH95218.1, ECO:0000313|Proteomes:UP000186455};
RN [1] {ECO:0000313|EMBL:OKH95218.1, ECO:0000313|Proteomes:UP000186455}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DCA2648 {ECO:0000313|EMBL:OKH95218.1,
RC ECO:0000313|Proteomes:UP000186455};
RA Yan X., Huang T., Ge H., Shen B.;
RT "Cloning and characterization of the uncialamcin biosynthetic gene
RT cluster.";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing alpha-L-rhamnose residues
CC in alpha-L-rhamnosides.; EC=3.2.1.40;
CC Evidence={ECO:0000256|ARBA:ARBA00001445};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKH95218.1}.
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DR EMBL; LFBV01000002; OKH95218.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Q4VBJ2; -.
DR STRING; 1048205.AB852_10350; -.
DR Proteomes; UP000186455; Unassembled WGS sequence.
DR GO; GO:0030596; F:alpha-L-rhamnosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 1.50.10.10; -; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.60.420.10; Maltose phosphorylase, domain 3; 1.
DR InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR InterPro; IPR016007; Alpha_rhamnosid.
DR InterPro; IPR035396; Bac_rhamnosid6H.
DR InterPro; IPR035398; Bac_rhamnosid_C.
DR InterPro; IPR013737; Bac_rhamnosid_N.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR008902; Rhamnosid_concanavalin.
DR PANTHER; PTHR33307; ALPHA-RHAMNOSIDASE (EUROFUNG); 1.
DR PANTHER; PTHR33307:SF6; ALPHA-RHAMNOSIDASE (EUROFUNG)-RELATED; 1.
DR Pfam; PF05592; Bac_rhamnosid; 1.
DR Pfam; PF17389; Bac_rhamnosid6H; 1.
DR Pfam; PF17390; Bac_rhamnosid_C; 1.
DR Pfam; PF08531; Bac_rhamnosid_N; 1.
DR PIRSF; PIRSF010631; A-rhamnsds; 1.
DR SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:OKH95218.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000186455}.
FT DOMAIN 171..340
FT /note="Bacterial alpha-L-rhamnosidase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08531"
FT DOMAIN 350..440
FT /note="Alpha-L-rhamnosidase concanavalin-like"
FT /evidence="ECO:0000259|Pfam:PF05592"
FT DOMAIN 458..798
FT /note="Alpha-L-rhamnosidase six-hairpin glycosidase"
FT /evidence="ECO:0000259|Pfam:PF17389"
FT DOMAIN 800..870
FT /note="Alpha-L-rhamnosidase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF17390"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 905 AA; 99638 MW; 5041459DB7FF1CFD CRC64;
MPSPRDPAAS ENTGPDGPLR VVNTSVEHTE NLLGTDVRRP RLGWELSAEG QRGARQSAYQ
VRVARSAAAL GDGLRTVWDS GRVVSERTFG VPYDGPGLEA RTRYHWQVRV WDGAGRVSRW
SAVRWWETAL PSDGWHGHWI GAGPAGGSGD GEVTARPAPL LRREFTVGAP VTRARLYISG
LAYYEAEING RRVGEQVLDP GFTDYDATVL YAVHDITGLI RPGGNAIGVT LGRGFFGMTT
PNVWNWHRPP WHGEPRLLAQ LEIDHPDGTR TLVATDGSWR ITEGPTRTDC LYAGETYDAR
LAPGGWSLPG YDDSAWSPAG RRRAPLGTVR AQPHEPIEVT GTVEPVAVRE TPGGSHVVDL
GRTLAGWSRL TVRAPAGTVV RLTYGEKLHD DGTVFAETEH VPGRFQRDEY VCAGTGGDEV
WEPRFSYKGF RYVEVSGVPA LRGRWSVVGR EVRTPVAEVS GFRCSEEFYE QLDRAMRRTV
RSNLHGIPTD TPMYEKNGWT GDAQLGVPVM TYAFGTHRLL AKWLGDLRDS QRPDGQLPVI
VPSGGWGYED LAPSPEWTTV YPFLVREMYR VYGDERAVRE HWRPVTRYLD WEIARLRDGL
AVTELGDYLA PGYGGNPPED TRLTATAYLY RALLATAELA GLVDDLDAPD QDATAARYRR
TAHELREAFN AAFLGPAGHY RTDRDPGYRQ TSNCVPLAFG LVPPHARESV TASLVADIAA
RGGHLDTGAL GTSVLLPQLS ERGHPEVAHT LATRRTYPSW GYWFERGADT MWEMWQADSR
SRAHYFQGTV AQWLYENVAG LRPGDAGYGS FVVRPDGRAG VEWARTSIRT VRGEAGVEWS
GGSGAEPFRM SVRVPVGATA EVHVPVGPGP GTVAVSAHPD ARWVRVERGF QVFRVPQGRW
EFTAG
//
