ID A0A1Q4VK58_9ACTN Unreviewed; 380 AA.
AC A0A1Q4VK58;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=PPM-type phosphatase domain-containing protein {ECO:0000259|SMART:SM00331};
GN ORFNames=A6A06_28790 {ECO:0000313|EMBL:OKH98201.1};
OS Streptomyces sp. CB02923.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1718985 {ECO:0000313|EMBL:OKH98201.1, ECO:0000313|Proteomes:UP000185893};
RN [1] {ECO:0000313|EMBL:OKH98201.1, ECO:0000313|Proteomes:UP000185893}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB02923 {ECO:0000313|EMBL:OKH98201.1,
RC ECO:0000313|Proteomes:UP000185893};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKH98201.1}.
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DR EMBL; LWKZ01000027; OKH98201.1; -; Genomic_DNA.
DR RefSeq; WP_073767639.1; NZ_LWKZ01000027.1.
DR AlphaFoldDB; A0A1Q4VK58; -.
DR STRING; 1718985.A6A06_28790; -.
DR Proteomes; UP000185893; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR InterPro; IPR036457; PPM-type-like_dom_sf.
DR InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR PANTHER; PTHR43156:SF2; MULTIDOMAIN REGULATORY PROTEIN RV1364C; 1.
DR PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR Pfam; PF07228; SpoIIE; 1.
DR SMART; SM00331; PP2C_SIG; 1.
DR SUPFAM; SSF81606; PP2C-like; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000185893};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..380
FT /note="PPM-type phosphatase domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5039168084"
FT TRANSMEM 46..68
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 80..97
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 126..338
FT /note="PPM-type phosphatase"
FT /evidence="ECO:0000259|SMART:SM00331"
FT REGION 342..380
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 380 AA; 39208 MW; E0A1F58D9DB20D88 CRC64;
MREVRQGALL LLTAVAGAAV AACDLALGPD VSLAGLLLIG PLVAATRLEG ACTAVVSFAA
LLLGVAVAGH EHTLARTDQL LSLTVLAAAA AYATWASDRQ AALDNQLAGV AAAAQRAILR
PTSFRVSGAS VCARYRSAAP RAVIGGDLYA FADTPSGLRV LIGDVRGKGL EAVRLSAAAI
GHFRDCAYTR SNLAEVAEEV DRRLIDDLGP EDFITAVIAE ISPGRLRLVN CGHHPPLHLP
AAGPPVLLTP SEPTTPIGLL PLPRVQEVEL APGDRLLLYT DGLAEARDPD GTMLDLAGLL
PACSLPDLND AIEAVLSTMC RHTHGAQDDD VALVLVELEP SMPRQHHTPT TPAVTRTSAE
PPGGLADRAG CPSSSAAVSD
//
