ID A0A1Q4VLB9_9ACTN Unreviewed; 516 AA.
AC A0A1Q4VLB9;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Nickel transporter {ECO:0000313|EMBL:OKH98617.1};
GN ORFNames=A6A06_30340 {ECO:0000313|EMBL:OKH98617.1};
OS Streptomyces sp. CB02923.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1718985 {ECO:0000313|EMBL:OKH98617.1, ECO:0000313|Proteomes:UP000185893};
RN [1] {ECO:0000313|EMBL:OKH98617.1, ECO:0000313|Proteomes:UP000185893}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB02923 {ECO:0000313|EMBL:OKH98617.1,
RC ECO:0000313|Proteomes:UP000185893};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKH98617.1}.
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DR EMBL; LWKZ01000027; OKH98617.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Q4VLB9; -.
DR STRING; 1718985.A6A06_30340; -.
DR Proteomes; UP000185893; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR PANTHER; PTHR40659; NICKEL/COBALT EFFLUX SYSTEM RCNA; 1.
DR PANTHER; PTHR40659:SF1; NICKEL_COBALT EFFLUX SYSTEM RCNA; 1.
DR PROSITE; PS00018; EF_HAND_1; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000185893};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..516
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012772677"
FT TRANSMEM 246..267
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 288..314
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 320..340
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 410..432
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 438..463
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 490..508
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 203..222
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 349..403
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 361..385
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 386..403
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 516 AA; 52189 MW; 8E6317AEE0C894E1 CRC64;
MLAVALAAVL LLLVPAGPAS AHPLGNFTVS QYDGLAVRPG ELRVDHVEDL AEIPAAQQKA
RIDRDGNGVL SRTELAGWAG ERCRTAARGS GLTVDGRREQ LRATGATADT RPGQAGLPTL
RLECGLTARL PSDGRAALRF RAAEGDGAPG WREVTAQGDR TRLTASDVPA KSVSRRLTAY
PQEVLASPPA RRSAAVRAVA GGPALSDTAG SPPAAAPPAA SVLPRGADRW TQALTGLVAR
HDLTPAFAAL ALGTALLLGA LHALAPGHGK TMMAAAAAAG GRSSRRDVLA LGLSVTVTHT
LGVFGLGALI AAGSAAAPSV VAWLGVASGA LVAGAGALLL RRALRLRRHG HGHGHGHGHG
HEHGHGHEHG HSHGHEHDHG HDHSHGHQHS HGHHHHHHHH PARPGLRGTI LLGFAGGLVP
SPSAVVVLVG AAALGQAWFG FLLVVAYGAG LAATLAAAGL LAVRLTLRLG DRLAAGRGAG
ARLLSAAHRL APVGTAAVVL LLGCGLLLKG AATTLG
//
