ID A0A1Q4VME5_9ACTN Unreviewed; 699 AA.
AC A0A1Q4VME5;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=Oxidoreductase {ECO:0000313|EMBL:OKH98992.1};
GN ORFNames=A6A06_25665 {ECO:0000313|EMBL:OKH98992.1};
OS Streptomyces sp. CB02923.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1718985 {ECO:0000313|EMBL:OKH98992.1, ECO:0000313|Proteomes:UP000185893};
RN [1] {ECO:0000313|EMBL:OKH98992.1, ECO:0000313|Proteomes:UP000185893}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB02923 {ECO:0000313|EMBL:OKH98992.1,
RC ECO:0000313|Proteomes:UP000185893};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKH98992.1}.
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DR EMBL; LWKZ01000026; OKH98992.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Q4VME5; -.
DR STRING; 1718985.A6A06_25665; -.
DR Proteomes; UP000185893; Unassembled WGS sequence.
DR GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR004104; Gfo/Idh/MocA-like_OxRdtase_C.
DR InterPro; IPR000683; Gfo/Idh/MocA-like_OxRdtase_N.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43818; BCDNA.GH03377; 1.
DR PANTHER; PTHR43818:SF11; BCDNA.GH03377; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR Pfam; PF01408; GFO_IDH_MocA; 1.
DR Pfam; PF02894; GFO_IDH_MocA_C; 1.
DR SUPFAM; SSF55347; Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000185893}.
FT DOMAIN 139..246
FT /note="Alcohol dehydrogenase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00107"
FT DOMAIN 344..455
FT /note="Gfo/Idh/MocA-like oxidoreductase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01408"
FT DOMAIN 475..690
FT /note="Gfo/Idh/MocA-like oxidoreductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02894"
FT REGION 296..339
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 615..637
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 699 AA; 72422 MW; DB3459204A52EE35 CRC64;
MVLTGAGRCD VIERDEPAGG PGEIVVDISV SVISPGTERA VLLDLPTADA RFPEYPGYMA
AGAVRAPSSL PGGTRVAVRR ARHGDVAAVP AACVRAVPDH VPLLDAAVWQ LALTALHGLE
RGAQCPGEPV TVIGGGLLGV ITRRLAAARG APEVRAVAGS AAKAWAAETE PATTFLSTGT
VGGGTPLVLD VTGSGAGLHT AVAAAADGGR VVLLGSPRSD LADVPLRQLY DRRLDLRGAH
VSRVGTEEEN RLGNVFFELL ARGLFTVRDV LAEYPATEAP AVYRRLATDR TLVSAALRWG
PDPPPGSSAA STGTAPESGP SGPVPRQAPA TAASPRRTPV PSPLRFGLIG CGDIGIEDAR
ALADAEGACL TACHDPVRQL AEDTVARYGG THEQALGRLM ARRDVDAVII ATPHDTHEPL
LAAALAAGKH VLLEKPLAQD LTTARRMASA AAGAGGLTTG VLFPTRTDPR FLRARETIGA
GAIGVPLGVS AHYLVDRSAD YFRGGLSGRS PSTWRLSKAR SGGGFLIMNL IHQIDTVRAL
LGREADRVYA ETATSPLADA PDIEDAVTLV IRFGRVIATL TGASRVVGGD GQHIRVWGDQ
GHLQVLPRYA VTHRRREAAP APGARRHPAP PEAAPAKPTA IDLRAWAFTG FARSVREGAP
VDVSLHDALR TQAVVEAAYA SARSGRATVP VLPTTEGGP
//
