ID A0A1Q4VRH3_9ACTN Unreviewed; 444 AA.
AC A0A1Q4VRH3;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 13.
DE SubName: Full=Transcriptional regulator {ECO:0000313|EMBL:OKI00430.1};
GN ORFNames=A6A06_24085 {ECO:0000313|EMBL:OKI00430.1};
OS Streptomyces sp. CB02923.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1718985 {ECO:0000313|EMBL:OKI00430.1, ECO:0000313|Proteomes:UP000185893};
RN [1] {ECO:0000313|EMBL:OKI00430.1, ECO:0000313|Proteomes:UP000185893}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB02923 {ECO:0000313|EMBL:OKI00430.1,
RC ECO:0000313|Proteomes:UP000185893};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- SIMILARITY: Belongs to the LytR/CpsA/Psr (LCP) family.
CC {ECO:0000256|ARBA:ARBA00006068}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKI00430.1}.
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DR EMBL; LWKZ01000025; OKI00430.1; -; Genomic_DNA.
DR RefSeq; WP_073766043.1; NZ_LWKZ01000025.1.
DR AlphaFoldDB; A0A1Q4VRH3; -.
DR STRING; 1718985.A6A06_24085; -.
DR OrthoDB; 9782542at2; -.
DR Proteomes; UP000185893; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.30.70.2390; -; 1.
DR Gene3D; 3.40.630.190; LCP protein; 1.
DR InterPro; IPR027381; LytR/CpsA/Psr_C.
DR InterPro; IPR004474; LytR_CpsA_psr.
DR NCBIfam; TIGR00350; lytR_cpsA_psr; 1.
DR PANTHER; PTHR33392; POLYISOPRENYL-TEICHOIC ACID--PEPTIDOGLYCAN TEICHOIC ACID TRANSFERASE TAGU; 1.
DR PANTHER; PTHR33392:SF6; POLYISOPRENYL-TEICHOIC ACID--PEPTIDOGLYCAN TEICHOIC ACID TRANSFERASE TAGU; 1.
DR Pfam; PF13399; LytR_C; 1.
DR Pfam; PF03816; LytR_cpsA_psr; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000185893};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 85..247
FT /note="Cell envelope-related transcriptional attenuator"
FT /evidence="ECO:0000259|Pfam:PF03816"
FT DOMAIN 352..440
FT /note="LytR/CpsA/Psr regulator C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13399"
SQ SEQUENCE 444 AA; 46896 MW; 7A0B6EBC687A277A CRC64;
MTRRGRILAW TGGIIGVLLL ITAGVGGWVY FKLDGNIHGA DVGSRLGGDR PANLSPGSKN
ILVVGSDSRA GANAKYGKNL ETMQSDTLMV LHIAANREWA TALSFPRDSW VSIPSCDSGN
GRKSKPHHFK INEAFTIGGE SGDVANAAAC TIKTVEKNTG LRIDHFTSVD FQGFKGMVNA
LGGIEVCPKT AIHDKKAHLD MEAGCQNVQD EKALGYVRTR YSVGDGSDLG RIARQQEFMK
ALGEKAQSKL ASPGALYDFL DSATKSITTD EDLAGIKPLS ELASTVKDIP SDRLTFLTVP
NYSREADVPT DKANVVWQYP QAGDLFSDLA HDKEVDKDKV AAAAKNLVTA RSVKVRVLNG
TGKTGYAAEV AAALRKLGFT VVSTDNAPPG TNETAITYPA SLEAQAKVLS ARLAGVKTEK
SPDATAANPG VVTLTVGEGF STTG
//
