ID A0A1Q4VWV0_9ACTN Unreviewed; 348 AA.
AC A0A1Q4VWV0;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Polyprenyl diphosphate synthase {ECO:0008006|Google:ProtNLM};
GN ORFNames=A6A06_14630 {ECO:0000313|EMBL:OKI02288.1};
OS Streptomyces sp. CB02923.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1718985 {ECO:0000313|EMBL:OKI02288.1, ECO:0000313|Proteomes:UP000185893};
RN [1] {ECO:0000313|EMBL:OKI02288.1, ECO:0000313|Proteomes:UP000185893}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB02923 {ECO:0000313|EMBL:OKI02288.1,
RC ECO:0000313|Proteomes:UP000185893};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC {ECO:0000256|ARBA:ARBA00006706, ECO:0000256|RuleBase:RU004466}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKI02288.1}.
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DR EMBL; LWKZ01000023; OKI02288.1; -; Genomic_DNA.
DR RefSeq; WP_073762872.1; NZ_LWKZ01000023.1.
DR AlphaFoldDB; A0A1Q4VWV0; -.
DR STRING; 1718985.A6A06_14630; -.
DR Proteomes; UP000185893; Unassembled WGS sequence.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR CDD; cd00685; Trans_IPPS_HT; 1.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR000092; Polyprenyl_synt.
DR InterPro; IPR033749; Polyprenyl_synt_CS.
DR PANTHER; PTHR12001; GERANYLGERANYL PYROPHOSPHATE SYNTHASE; 1.
DR PANTHER; PTHR12001:SF69; GERANYLGERANYL PYROPHOSPHATE SYNTHASE; 1.
DR Pfam; PF00348; polyprenyl_synt; 1.
DR SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR SFLD; SFLDG01017; Polyprenyl_Transferase_Like; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
DR PROSITE; PS00723; POLYPRENYL_SYNTHASE_1; 1.
DR PROSITE; PS00444; POLYPRENYL_SYNTHASE_2; 1.
PE 3: Inferred from homology;
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Reference proteome {ECO:0000313|Proteomes:UP000185893};
KW Transferase {ECO:0000256|RuleBase:RU004466}.
SQ SEQUENCE 348 AA; 35799 MW; A0FE17F83DC39CB0 CRC64;
MDRAFVAAAS PEDAGLILLE QAGHRVRPVL ERQVTGRLNQ VEKHAGYHLG WQDEKGRPCA
GSSGKAVRPA LALASAKAVG GRSRDALTAA GAVQMVHEFS LLHDDIIDGD RTRRHRPTVW
SVFGVPAGIL TGDLLLSLAF TTLADGPLRA APDSLRCLAD AVTELVEGEA LDVAFERRRH
VSLSEYTAMA AAKTGALMAC ACTLGALAGG AGRERAQLLG AFGRHLGVAF QIVDDLLGLQ
GDPAVTGKPV GADLAAGKKT MPLLAALASG TRQGQELAAL LAGSASPEGA VPARAALLVA
EAGGVSAARS AVHGELTSAF AALAEAVPTG ADRDELRALA HVLTRRNH
//
