ID A0A1Q4VWX7_9ACTN Unreviewed; 742 AA.
AC A0A1Q4VWX7;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=Xanthine dehydrogenase {ECO:0000313|EMBL:OKI02326.1};
GN ORFNames=A6A06_14855 {ECO:0000313|EMBL:OKI02326.1};
OS Streptomyces sp. CB02923.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1718985 {ECO:0000313|EMBL:OKI02326.1, ECO:0000313|Proteomes:UP000185893};
RN [1] {ECO:0000313|EMBL:OKI02326.1, ECO:0000313|Proteomes:UP000185893}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB02923 {ECO:0000313|EMBL:OKI02326.1,
RC ECO:0000313|Proteomes:UP000185893};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKI02326.1}.
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DR EMBL; LWKZ01000023; OKI02326.1; -; Genomic_DNA.
DR RefSeq; WP_073762913.1; NZ_LWKZ01000023.1.
DR AlphaFoldDB; A0A1Q4VWX7; -.
DR STRING; 1718985.A6A06_14855; -.
DR OrthoDB; 8428274at2; -.
DR Proteomes; UP000185893; Unassembled WGS sequence.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 3.90.1170.50; Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead; 1.
DR Gene3D; 3.30.365.10; Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain; 4.
DR InterPro; IPR000674; Ald_Oxase/Xan_DH_a/b.
DR InterPro; IPR036856; Ald_Oxase/Xan_DH_a/b_sf.
DR InterPro; IPR016208; Ald_Oxase/xanthine_DH-like.
DR InterPro; IPR008274; AldOxase/xan_DH_MoCoBD1.
DR InterPro; IPR046867; AldOxase/xan_DH_MoCoBD2.
DR InterPro; IPR037165; AldOxase/xan_DH_Mopterin-bd_sf.
DR PANTHER; PTHR11908:SF153; DEHYDROGENASE; 1.
DR PANTHER; PTHR11908; XANTHINE DEHYDROGENASE; 1.
DR Pfam; PF01315; Ald_Xan_dh_C; 1.
DR Pfam; PF02738; MoCoBD_1; 1.
DR Pfam; PF20256; MoCoBD_2; 1.
DR SMART; SM01008; Ald_Xan_dh_C; 1.
DR SUPFAM; SSF54665; CO dehydrogenase molybdoprotein N-domain-like; 1.
DR SUPFAM; SSF56003; Molybdenum cofactor-binding domain; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000185893}.
FT DOMAIN 16..128
FT /note="Aldehyde oxidase/xanthine dehydrogenase a/b
FT hammerhead"
FT /evidence="ECO:0000259|SMART:SM01008"
SQ SEQUENCE 742 AA; 79127 MW; 5F37FBE5BBA56DFD CRC64;
MIGRALNRVD GPSKVTGRAV YAYEQGDAGP PLYGVVVGAT IGKGRITRID TASAERAPGV
RMVMTHLNAP AQGSRDEPVA FEFWRAQPVL TGPDVHHHGD PVAFVVATAF EQAREAAGLV
RVEYATGQGR FDFAAHQSEV YVPKEVNAGL PTDTAVGDFA AGFDSAPVKI DQRYTTPYEF
SMPMEPHACL AVPRGEDLIV HVSCQIVDAA RASIAGTLGI DPVRVHVVTP FVGGGFGSKL
GIHCETVLAA LAARALRRPV KVALTRQQIF QLVGMRPTSS QRVRLGAGRD GRLAAIAHDV
TMNTNPALEY AEQTAATTRS LYAAPHRATS HRLTTLDLPR GADVRAPGEA PGLLAVESAM
DELADALDMD PVELRIRNEP AVDPERGVPY SDRHLVDCLR EGARRFGWER RPTTPASARE
GRWLVGYGMS AAIRGHFQTP TTVRVRVDAD GTAVVQTDMT DLGTGTYTIL TQVAADGLGL
PPDRVRTELG RSEFPRSWGS GGSWGATNSS TATDRACADL RAKLLDAVRT DTRSPLYGLD
PADAVFREGR VRVGHASEPL GELVRRHHPH GLEAVGETLF MGDDPNYTAY SIHTYGAHFA
EVGVDADTAE IRLRRMLGVF SVGRVLNPKT ARSQLIGGMI WGIGAALEEE AVVDPRTGAF
VNRDLAQYLV PVHADVPDVD AVILDGYDGK ANALGAKGVG ELGICGAGAA VANAVYNATG
VRVRDFPVTL EKVLPGLPSM DS
//
