ID A0A1Q4W728_9ACTN Unreviewed; 307 AA.
AC A0A1Q4W728;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=LysR family transcriptional regulator {ECO:0000313|EMBL:OKI05794.1};
GN ORFNames=AMK13_21135 {ECO:0000313|EMBL:OKI05794.1};
OS Streptomyces sp. CB02056.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1703924 {ECO:0000313|EMBL:OKI05794.1, ECO:0000313|Proteomes:UP000186379};
RN [1] {ECO:0000313|EMBL:OKI05794.1, ECO:0000313|Proteomes:UP000186379}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB02056 {ECO:0000313|EMBL:OKI05794.1,
RC ECO:0000313|Proteomes:UP000186379};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000256|ARBA:ARBA00009437}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKI05794.1}.
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DR EMBL; LIPD01000007; OKI05794.1; -; Genomic_DNA.
DR RefSeq; WP_074003639.1; NZ_LIPD01000007.1.
DR AlphaFoldDB; A0A1Q4W728; -.
DR OrthoDB; 3181812at2; -.
DR Proteomes; UP000186379; Unassembled WGS sequence.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd05466; PBP2_LTTR_substrate; 1.
DR Gene3D; 3.40.190.290; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30346:SF16; SMALL NEUTRAL PROTEASE REGULATORY PROTEIN; 1.
DR PANTHER; PTHR30346; TRANSCRIPTIONAL DUAL REGULATOR HCAR-RELATED; 1.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR PRINTS; PR00039; HTHLYSR.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000186379}.
FT DOMAIN 1..58
FT /note="HTH lysR-type"
FT /evidence="ECO:0000259|PROSITE:PS50931"
SQ SEQUENCE 307 AA; 32956 MW; 2191E59D80EC7F6F CRC64;
MQLQQLRYFL AVAETRHFTR AAEAAHVAQP SLSQQIRALE RELGAELFHR TRGNIALTDA
GDALLPLARR ILADTETARL AVQETVQLRR GRVRLGAPPS LCTSLVPDVL RVFRDRYPGV
ALVVREGGSR DLVGWLAAGE LDLALTITRP SGEQEPALAV TELLHEELVL VAAGRPARRK
VRVTELKGRP LVMFREGYDV REATLAACRA AGFEPEFAVE GGEMDAVLGF VRAGIGPAVV
PGMVAARSGL AVTAFAGPGL GRTIAVAHGH EVPLTRAAEA LRDTLLAHLR DAARDGELPP
GTRLLLP
//
