ID   A0A1Q4WGV0_9ACTN        Unreviewed;       523 AA.
AC   A0A1Q4WGV0;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   24-JAN-2024, entry version 21.
DE   RecName: Full=Maltokinase {ECO:0000256|ARBA:ARBA00013882};
DE            EC=2.7.1.175 {ECO:0000256|ARBA:ARBA00011962};
DE   AltName: Full=Maltose-1-phosphate synthase {ECO:0000256|ARBA:ARBA00031251};
GN   ORFNames=A6A06_00575 {ECO:0000313|EMBL:OKI09251.1};
OS   Streptomyces sp. CB02923.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1718985 {ECO:0000313|EMBL:OKI09251.1, ECO:0000313|Proteomes:UP000185893};
RN   [1] {ECO:0000313|EMBL:OKI09251.1, ECO:0000313|Proteomes:UP000185893}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CB02923 {ECO:0000313|EMBL:OKI09251.1,
RC   ECO:0000313|Proteomes:UP000185893};
RX   PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA   Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA   Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA   Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT   "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL   MBio 7:e02104-e02116(2016).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + D-maltose = ADP + alpha-maltose 1-phosphate + H(+);
CC         Xref=Rhea:RHEA:31915, ChEBI:CHEBI:15378, ChEBI:CHEBI:17306,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:63576, ChEBI:CHEBI:456216;
CC         EC=2.7.1.175; Evidence={ECO:0000256|ARBA:ARBA00001537};
CC   -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC       {ECO:0000256|ARBA:ARBA00004964}.
CC   -!- SUBUNIT: Monomer. {ECO:0000256|ARBA:ARBA00011245}.
CC   -!- SIMILARITY: Belongs to the aminoglycoside phosphotransferase family.
CC       {ECO:0000256|ARBA:ARBA00006219}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OKI09251.1}.
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DR   EMBL; LWKZ01000001; OKI09251.1; -; Genomic_DNA.
DR   RefSeq; WP_073757674.1; NZ_LWKZ01000001.1.
DR   AlphaFoldDB; A0A1Q4WGV0; -.
DR   STRING; 1718985.A6A06_00575; -.
DR   OrthoDB; 3787729at2; -.
DR   UniPathway; UPA00164; -.
DR   Proteomes; UP000185893; Unassembled WGS sequence.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.90.1200.10; -; 1.
DR   InterPro; IPR002575; Aminoglycoside_PTrfase.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR040999; Mak_N_cap.
DR   Pfam; PF01636; APH; 1.
DR   Pfam; PF18085; Mak_N_cap; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE   3: Inferred from homology;
KW   Kinase {ECO:0000313|EMBL:OKI09251.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000185893};
KW   Transferase {ECO:0000313|EMBL:OKI09251.1}.
FT   DOMAIN          35..153
FT                   /note="Maltokinase N-terminal cap"
FT                   /evidence="ECO:0000259|Pfam:PF18085"
FT   DOMAIN          191..449
FT                   /note="Aminoglycoside phosphotransferase"
FT                   /evidence="ECO:0000259|Pfam:PF01636"
FT   REGION          82..109
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          497..523
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        86..101
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   523 AA;  55661 MW;  90ABFE0B176B04AA CRC64;
     MSETASTRAI RSTHDRLSIT APALLSSLVP LLSEWLPRQR WFAGKGRPIT GFQLVSATEL
     LPCAAGGATP GLLHLLVRAQ QSAAPAGPPH PAPPENPADQ AAAPPGSPAA TADCYQLLLG
     VHSALPPQLA PAVIGRPGGG PLHGRTVYDA LLDNRLCALL LERLRVPGRL GGLRFCRVAD
     STISSGMPAR PVTAEQTNSS VIYGDSYILK VFRRTAPGLN PDLELPLALA RAKCGRVPPP
     AAWFETDPEA GEGEPVTLGV LQPFLSGSAD GWQLALNALA VQADFTSSAR ALGHATAEVH
     TALAETLPTT ELRRPQLDAI ATQMNERLVA TARVVPALRP YCSRLRTAFD ELAALGHDGR
     AWSAQRIHGD LHLGQTLRSA DEGRWSLIDF EGEPSRPLAE RRRPQPAVRD VAAMLRSFDY
     AARSGPSGGD PWSLEWARRT RAAYCLGYAE AGGLDPRSAP ELMRAYETDK AVYEVLYEAR
     HRPNWLPVPM AAVRRLAGAQ ASRGATGTDP GAGPDLDVAD GRA
//