ID A0A1Q4WH41_9ACTN Unreviewed; 354 AA.
AC A0A1Q4WH41;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE SubName: Full=NAD-dependent epimerase {ECO:0000313|EMBL:OKI09345.1};
GN ORFNames=A6A06_01115 {ECO:0000313|EMBL:OKI09345.1};
OS Streptomyces sp. CB02923.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1718985 {ECO:0000313|EMBL:OKI09345.1, ECO:0000313|Proteomes:UP000185893};
RN [1] {ECO:0000313|EMBL:OKI09345.1, ECO:0000313|Proteomes:UP000185893}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB02923 {ECO:0000313|EMBL:OKI09345.1,
RC ECO:0000313|Proteomes:UP000185893};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKI09345.1}.
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DR EMBL; LWKZ01000001; OKI09345.1; -; Genomic_DNA.
DR RefSeq; WP_073757868.1; NZ_LWKZ01000001.1.
DR AlphaFoldDB; A0A1Q4WH41; -.
DR STRING; 1718985.A6A06_01115; -.
DR OrthoDB; 7941246at2; -.
DR Proteomes; UP000185893; Unassembled WGS sequence.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR001509; Epimerase_deHydtase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR12126:SF11; NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 9, MITOCHONDRIAL; 1.
DR PANTHER; PTHR12126; NADH-UBIQUINONE OXIDOREDUCTASE 39 KDA SUBUNIT-RELATED; 1.
DR Pfam; PF01370; Epimerase; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000185893}.
FT DOMAIN 3..229
FT /note="NAD-dependent epimerase/dehydratase"
FT /evidence="ECO:0000259|Pfam:PF01370"
SQ SEQUENCE 354 AA; 38358 MW; 6CFCD673450EC297 CRC64;
MRILVMGGTW FLGRAVVEEA LRRGWEVSTF NRGRSGQDVP GVRPVRGDRT AAEDLAELAS
HGPWDAVVDT SSAALPPKDV LTGARALKAA AERYVYVSTV NAYRGWPGDP LTEASELLDG
PPDADADYGR LPEDWTGPDW YYGRQKAGAE RAVLEAFGEK CSVLLRPGVI LGPGEYVGRL
PWWLRRAERG GRVLAPGLPG KSIQPVDVRD VAVFALDQAA APVGGAYNVV APIGRETMGG
FLNACLEVTG HRGELSWVPD AFLVKAGVEQ WTELPLWRTH AGVWNIASDG AQAAGLVCRP
LAETVEATWR WLRDGGLPVA HPRADEHGIA ARKEERLLEE FAERVASGFE GERL
//
