ID A0A1Q4WK27_9ACTN Unreviewed; 360 AA.
AC A0A1Q4WK27;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=GDSL family lipase {ECO:0000313|EMBL:OKI10448.1};
GN ORFNames=AMK13_04770 {ECO:0000313|EMBL:OKI10448.1};
OS Streptomyces sp. CB02056.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1703924 {ECO:0000313|EMBL:OKI10448.1, ECO:0000313|Proteomes:UP000186379};
RN [1] {ECO:0000313|EMBL:OKI10448.1, ECO:0000313|Proteomes:UP000186379}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB02056 {ECO:0000313|EMBL:OKI10448.1,
RC ECO:0000313|Proteomes:UP000186379};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKI10448.1}.
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DR EMBL; LIPD01000002; OKI10448.1; -; Genomic_DNA.
DR RefSeq; WP_074001304.1; NZ_LIPD01000002.1.
DR AlphaFoldDB; A0A1Q4WK27; -.
DR OrthoDB; 9804395at2; -.
DR Proteomes; UP000186379; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01836; FeeA_FeeB_like; 1.
DR Gene3D; 3.40.50.1110; SGNH hydrolase; 1.
DR InterPro; IPR013830; SGNH_hydro.
DR InterPro; IPR036514; SGNH_hydro_sf.
DR PANTHER; PTHR30383; THIOESTERASE 1/PROTEASE 1/LYSOPHOSPHOLIPASE L1; 1.
DR PANTHER; PTHR30383:SF5; THIOESTERASE 1_PROTEASE 1_LYSOPHOSPHOLIPASE L1; 1.
DR Pfam; PF13472; Lipase_GDSL_2; 1.
DR SUPFAM; SSF52266; SGNH hydrolase; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000186379};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 15..38
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 81..256
FT /note="SGNH hydrolase-type esterase"
FT /evidence="ECO:0000259|Pfam:PF13472"
FT REGION 325..360
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 343..360
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 360 AA; 36058 MW; 20D66C7F4261F9B5 CRC64;
MPGARDSRAR VARRIATAAA YGGGGLGLLG VGVVGLLVTE SRLAIQAIGV LETVPPKADG
VYGEAFADRA ADPQAPLVLA VLGDSTGAGL GVARAGETPG ALLAAGLASV AERPVRLVNV
ARSGGRSADL SGQLEQALPH HPDVAVIMVG ANDVTRHSPA QLAVRQLGEA VAALRANGCE
VVVGTCPDLG TIKPVRPPLR WVARRLSRQL AAAQTIAVVE AGGRTVSLGS LLGPEFAARP
EMFAADRYHP SAQGYATAAM AVLPSVCAAL GLWPEEERPA TAVPGGTVLP VAVAAATAAG
REGTEVAAVP AEGAGRRWAQ LRQRLRIGLP GPESGKEPGT TPDGGPGNTS ASSHAAAGDA
//
