ID A0A1Q4WQ56_9ACTN Unreviewed; 300 AA.
AC A0A1Q4WQ56;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE SubName: Full=Serine hydrolase {ECO:0000313|EMBL:OKI12262.1};
GN ORFNames=A6A08_16955 {ECO:0000313|EMBL:OKI12262.1};
OS Nocardiopsis sp. TSRI0078.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Nocardiopsaceae; Nocardiopsis.
OX NCBI_TaxID=1718951 {ECO:0000313|EMBL:OKI12262.1, ECO:0000313|Proteomes:UP000185866};
RN [1] {ECO:0000313|EMBL:OKI12262.1, ECO:0000313|Proteomes:UP000185866}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TSRI0078 {ECO:0000313|EMBL:OKI12262.1,
RC ECO:0000313|Proteomes:UP000185866};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKI12262.1}.
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DR EMBL; LWLB01000037; OKI12262.1; -; Genomic_DNA.
DR RefSeq; WP_073705278.1; NZ_LWLB01000037.1.
DR AlphaFoldDB; A0A1Q4WQ56; -.
DR STRING; 1718951.A6A08_16955; -.
DR OrthoDB; 33989at2; -.
DR Proteomes; UP000185866; Unassembled WGS sequence.
DR GO; GO:0008800; F:beta-lactamase activity; IEA:InterPro.
DR GO; GO:0030655; P:beta-lactam antibiotic catabolic process; IEA:InterPro.
DR GO; GO:0046677; P:response to antibiotic; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR045155; Beta-lactam_cat.
DR InterPro; IPR000871; Beta-lactam_class-A.
DR PANTHER; PTHR35333; BETA-LACTAMASE; 1.
DR PANTHER; PTHR35333:SF4; SLR0121 PROTEIN; 1.
DR Pfam; PF13354; Beta-lactamase2; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:OKI12262.1}.
FT DOMAIN 22..270
FT /note="Beta-lactamase class A catalytic"
FT /evidence="ECO:0000259|Pfam:PF13354"
SQ SEQUENCE 300 AA; 32246 MW; 5C339209536B0E6A CRC64;
MSATALIREL RGELDEAGLR GSFLVRDLST GEELGIEPDL EFSTASLVKV PLAVATLERV
RSGEIDGAEQ LLVQPGRSAV PGHTGLTKFR HPVRVSVEDL VYLSTCLSDN TATDVLFDLT
PPARVAESLR AAGLRGITVR QTIRDIGDTP ANRLDPDEVH LAHLLAIGEG TAGRGHRIAQ
LDVTRASSGS ARAFADLLEA LWRPSAIDPD VAARVRELMG DNVLRHRLAP DFASDASRWF
SKTGSLLNLR HEVGVVEHAD GQAFAVAVLT ESRVPAFQQP GAEALMARVA RSLRDHLRAG
//
