ID A0A1Q4WQH7_9ACTN Unreviewed; 282 AA.
AC A0A1Q4WQH7;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE SubName: Full=Serine hydrolase {ECO:0000313|EMBL:OKI12382.1};
GN ORFNames=A6A08_17650 {ECO:0000313|EMBL:OKI12382.1};
OS Nocardiopsis sp. TSRI0078.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Nocardiopsaceae; Nocardiopsis.
OX NCBI_TaxID=1718951 {ECO:0000313|EMBL:OKI12382.1, ECO:0000313|Proteomes:UP000185866};
RN [1] {ECO:0000313|EMBL:OKI12382.1, ECO:0000313|Proteomes:UP000185866}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TSRI0078 {ECO:0000313|EMBL:OKI12382.1,
RC ECO:0000313|Proteomes:UP000185866};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKI12382.1}.
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DR EMBL; LWLB01000037; OKI12382.1; -; Genomic_DNA.
DR RefSeq; WP_073705399.1; NZ_LWLB01000037.1.
DR AlphaFoldDB; A0A1Q4WQH7; -.
DR STRING; 1718951.A6A08_17650; -.
DR Proteomes; UP000185866; Unassembled WGS sequence.
DR GO; GO:0008800; F:beta-lactamase activity; IEA:InterPro.
DR GO; GO:0030655; P:beta-lactam antibiotic catabolic process; IEA:InterPro.
DR GO; GO:0046677; P:response to antibiotic; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR045155; Beta-lactam_cat.
DR InterPro; IPR000871; Beta-lactam_class-A.
DR PANTHER; PTHR35333; BETA-LACTAMASE; 1.
DR PANTHER; PTHR35333:SF4; SLR0121 PROTEIN; 1.
DR Pfam; PF13354; Beta-lactamase2; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:OKI12382.1}.
FT DOMAIN 11..240
FT /note="Beta-lactamase class A catalytic"
FT /evidence="ECO:0000259|Pfam:PF13354"
SQ SEQUENCE 282 AA; 29788 MW; D3AA2201D8DDFC1D CRC64;
MNTTSAPAVR VHAREVDGTG QVGHGAEDPV VLASVAKVLI VLEFARQAST GLVDPTERVV
VRRDARLGGW GTADFADDVE LSLRDCALLA MTISDNTAAD LIVDRVGVEP VQLLAAELGL
ERTRFTGGPR ALLHALLDES DATGTDPAVL LARDPSRTTS STLADITRLL QLVWTDAAAP
PRACAFVRDL MARQLVRTRI ASGFGPDVRV GVKSGTLPGL RMEAGVVEYP DGGRYAVAVC
AVGPDPDRTA LEADMALGRA AREAVERLRV RFRTAGGTSA RC
//
