ID A0A1Q4XJT2_9ACTN Unreviewed; 686 AA.
AC A0A1Q4XJT2;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=Diguanylate phosphodiesterase {ECO:0000313|EMBL:OKI22514.1};
GN ORFNames=A6A08_19855 {ECO:0000313|EMBL:OKI22514.1};
OS Nocardiopsis sp. TSRI0078.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Nocardiopsaceae; Nocardiopsis.
OX NCBI_TaxID=1718951 {ECO:0000313|EMBL:OKI22514.1, ECO:0000313|Proteomes:UP000185866};
RN [1] {ECO:0000313|EMBL:OKI22514.1, ECO:0000313|Proteomes:UP000185866}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TSRI0078 {ECO:0000313|EMBL:OKI22514.1,
RC ECO:0000313|Proteomes:UP000185866};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- SIMILARITY: Belongs to the CdaR family.
CC {ECO:0000256|ARBA:ARBA00006754}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKI22514.1}.
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DR EMBL; LWLB01000003; OKI22514.1; -; Genomic_DNA.
DR RefSeq; WP_073701441.1; NZ_LWLB01000003.1.
DR AlphaFoldDB; A0A1Q4XJT2; -.
DR STRING; 1718951.A6A08_19855; -.
DR OrthoDB; 8026818at2; -.
DR Proteomes; UP000185866; Unassembled WGS sequence.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 1.10.10.2840; PucR C-terminal helix-turn-helix domain; 1.
DR InterPro; IPR041522; CdaR_GGDEF.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR025736; PucR_C-HTH_dom.
DR InterPro; IPR042070; PucR_C-HTH_sf.
DR PANTHER; PTHR33744; CARBOHYDRATE DIACID REGULATOR; 1.
DR PANTHER; PTHR33744:SF1; CONSERVED PROTEIN; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF17853; GGDEF_2; 1.
DR Pfam; PF13556; HTH_30; 1.
DR SMART; SM00065; GAF; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
PE 3: Inferred from homology;
FT DOMAIN 119..270
FT /note="GAF"
FT /evidence="ECO:0000259|SMART:SM00065"
FT REGION 1..42
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 334..361
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 686 AA; 71882 MW; D3A6D4CC3DD9CE51 CRC64;
MERELNTTTS GTPDPDAPGA VVPGAVSPGP EDPGGGGPAG SEGQAFFLDL LLRDAPAVEY
ERPVLRARAR GEDPEVVAAL EAAKLTALRV RSVMRDRQRR ESELSALFET ANDLAGMRSL
DQVLQAIVER ARNLLGTDIA YLTLSDPEAG GTYMRVTSGS VSASFQRLRL APGRGLGGLV
ATTALPYVTA NYFADPRFVH ADNIDHAVRE EGLVAILGVP LKMNGRDVGV LFAANRRERP
FAHSEVALLS SLAAHAAIAI DSANLIDDTR RALDELHTVN ERLQRHTASV ERSAAAHDRL
TDLVLRGGGV REVAAAVAEV LGGTVLIHDA TSDESVTAGP QGAVEESARG GTPWDSGDGG
LADAVRSSLA SGRAVRAGRA WVASAAAGTE PLGTLVLRGV ELDSTDQRVL ERAAMVTALL
LLIRRSVSET ELRVRGDLLD ELLEVPARDP VSLRQRASLL RADLDGPHVL VVAEAPGADP
GRLRSAATHV AETTGGLAGS RSGRLVLALP GTGPSAVGRR VADELSAAAN GPVTAGLAGP
TDGPASFRDA FAEASRCLQT LRALGREGGV ATTEDLGFSG LLLSQDRDVP GFVSATLGPL
LEYDARRGTL LVETLRAYFA AGGNLSRAKE ELHIHVNTVA QRLERIGQLI GADWQRPGRA
LELQLALHLH GLLDRGVDLS GDQDAG
//
