ID   A0A1Q4XVA7_9PSEU        Unreviewed;       982 AA.
AC   A0A1Q4XVA7;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=SARP family transcriptional regulator {ECO:0000313|EMBL:OKI26296.1};
GN   ORFNames=A6A25_31880 {ECO:0000313|EMBL:OKI26296.1};
OS   Saccharothrix sp. CB00851.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Saccharothrix.
OX   NCBI_TaxID=1835005 {ECO:0000313|EMBL:OKI26296.1, ECO:0000313|Proteomes:UP000186828};
RN   [1] {ECO:0000313|EMBL:OKI26296.1, ECO:0000313|Proteomes:UP000186828}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CB00851 {ECO:0000313|EMBL:OKI26296.1,
RC   ECO:0000313|Proteomes:UP000186828};
RX   PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA   Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA   Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA   Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT   "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL   MBio 7:e02104-e02116(2016).
CC   -!- SIMILARITY: Belongs to the AfsR/DnrI/RedD regulatory family.
CC       {ECO:0000256|ARBA:ARBA00005820}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OKI26296.1}.
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DR   EMBL; LWLC01000024; OKI26296.1; -; Genomic_DNA.
DR   RefSeq; WP_073893391.1; NZ_LWLC01000024.1.
DR   AlphaFoldDB; A0A1Q4XVA7; -.
DR   STRING; 1835005.A6A25_31880; -.
DR   Proteomes; UP000186828; Unassembled WGS sequence.
DR   GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0098542; P:defense response to other organism; IEA:UniProt.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd15831; BTAD; 1.
DR   CDD; cd00383; trans_reg_C; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR005158; BTAD.
DR   InterPro; IPR002182; NB-ARC.
DR   InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR35807:SF1; TRANSCRIPTIONAL REGULATOR REDD; 1.
DR   PANTHER; PTHR35807; TRANSCRIPTIONAL REGULATOR REDD-RELATED; 1.
DR   Pfam; PF03704; BTAD; 1.
DR   Pfam; PF00931; NB-ARC; 1.
DR   Pfam; PF13424; TPR_12; 1.
DR   Pfam; PF00486; Trans_reg_C; 1.
DR   PRINTS; PR00364; DISEASERSIST.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM01043; BTAD; 1.
DR   SMART; SM00028; TPR; 6.
DR   SMART; SM00862; Trans_reg_C; 1.
DR   SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF48452; TPR-like; 3.
DR   PROSITE; PS51755; OMPR_PHOB; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW   ProRule:PRU01091}; Reference proteome {ECO:0000313|Proteomes:UP000186828}.
FT   DOMAIN          1..95
FT                   /note="OmpR/PhoB-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51755"
FT   DNA_BIND        1..95
FT                   /note="OmpR/PhoB-type"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
SQ   SEQUENCE   982 AA;  105115 MW;  255E2B3B80A5D144 CRC64;
     MTLSQDEFGV LGALVVRRNG RSVPVTAAKH RIVLTTLLLD ANRSVPASDL IRRVWGDTPP
     DRAAQTLPVY VMRLRRALGE PPLIHTTPTG YRIDVPPAAL DLHRFEAAAE EGAKLAAAED
     FTASAEAYER ALSCWHGPPL ADVPSESLHE TEVPNLAEQR LRVISELTDV KLRLDRCDEV
     IADLRRLTAQ HPLRERFWSQ LMVALYRVDR QADALDAYRQ ASTALARELG VDPSDALRAV
     HHAILTGDPA LHQPAANTWA PVSQLPAPVG NFVGRGAELG RVTDLLTRGT ATVVVCGPPG
     VGKTAFAISV AHAVRDRYPD GQLYVNLRGH STSPPLPTSA VLARFLRAMG VRADHIPVDT
     QELVRGYQAR LRGRRVLITL DNAASVDQVL PLLPGDPGCS VLVTSRNELR LGAATVRLDV
     LRGDEAWKLL ARSLGSEAAV TQFDALGELA RLCGYLPLAL RIALGNLVGS SHVDVASYVE
     ELRGGDRLAV LAVDNDDTAA VRRAFDLSYA ALTPEAARLF RLAGLLPGPD FSVAGAAALL
     DAPEDVARGL LEDLASAHLV QRVGADRFAL HDLLHDYAAD RAAAAGEDLD AARRRLFDWY
     LRTAVEVGDV LYPELGASGP PRLDPDAARA WLEAERPSVL AATEHCAAHG PLPLAWRLID
     AVGGYFGSHG HHVEFVHAID AALGAARAAG DHDAETLMLV WLAAEHRNLG NLRAAQRYLR
     SARPSGRTVW LHAGLDGVVH LELGEFPAAF ASFERLMALS AEEWAGPHVR IGALAGLGAL
     RMMRGELEPA RSLLAEGLEL ARAADGANLE AACAALLGRC LTADGDHGRA VELLREALAA
     WHRTGARHAR AEAMAHLATA LCLGGGHAEA LRTAQRSLAL VQELGGSPRI ESEVHNALGL
     VLRHLGKPAR AVAAHLRALE LATSSDYRYG VARSHVHLIH ALAADGRRAE ALRHARVGHD
     LATRSGFNDC ATATATALTT LT
//