ID A0A1Q4Y2A2_9PSEU Unreviewed; 428 AA.
AC A0A1Q4Y2A2;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=Citrate transporter-like domain-containing protein {ECO:0000259|Pfam:PF03600};
GN ORFNames=A6A25_30740 {ECO:0000313|EMBL:OKI28594.1};
OS Saccharothrix sp. CB00851.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharothrix.
OX NCBI_TaxID=1835005 {ECO:0000313|EMBL:OKI28594.1, ECO:0000313|Proteomes:UP000186828};
RN [1] {ECO:0000313|EMBL:OKI28594.1, ECO:0000313|Proteomes:UP000186828}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB00851 {ECO:0000313|EMBL:OKI28594.1,
RC ECO:0000313|Proteomes:UP000186828};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CitM (TC 2.A.11) transporter family.
CC {ECO:0000256|ARBA:ARBA00009843}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKI28594.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LWLC01000021; OKI28594.1; -; Genomic_DNA.
DR RefSeq; WP_073892402.1; NZ_LWLC01000021.1.
DR AlphaFoldDB; A0A1Q4Y2A2; -.
DR STRING; 1835005.A6A25_30740; -.
DR Proteomes; UP000186828; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015105; F:arsenite transmembrane transporter activity; IEA:InterPro.
DR CDD; cd01116; P_permease; 1.
DR InterPro; IPR000802; Arsenical_pump_ArsB.
DR InterPro; IPR004680; Cit_transptr-like_dom.
DR PANTHER; PTHR43568; P PROTEIN; 1.
DR PANTHER; PTHR43568:SF1; P PROTEIN; 1.
DR Pfam; PF03600; CitMHS; 1.
DR PRINTS; PR00758; ARSENICPUMP.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000186828};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 28..48
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 60..86
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 98..126
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 138..155
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 175..197
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 225..245
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 251..269
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 281..303
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 315..333
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 403..424
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 14..369
FT /note="Citrate transporter-like"
FT /evidence="ECO:0000259|Pfam:PF03600"
SQ SEQUENCE 428 AA; 45938 MW; EC9F6CDCD0DFEBAD CRC64;
MSAVLALAIF LVAFFFIATE KADKLKVVLI ASGAMAILGL VPGAEVFFSE HAGIDWNVIF
LLFGMMVIVG IVKQTGIFDY LAIWAAKTAR GKPYRLMVML MAITAVASPF LDNVTTIMLV
VPVTIVVCNR LRIAPQPYVI AEVLASNIGG AATLIGDPPN IIIGSRAGLT FTDFLVHMAP
IVCVIFAVFV LLTRVLFRKS FQYNPDHVAA VMALNERRAI TDARMLRRCL AVFAVVVVGF
SLHSVLHLDP AIVALLGAGL MMLATGADVG DVLREVEWHT LAFFMGLFVM VAGLVHTGVI
ETIGSWAVQG VGDNYFLAAT ALLFGSSVLG AFFDNIPYAA TMSPIVEGIV AEVPDPATGQ
ALWWSFALGA DFSGNGTAVA ASANVVAIGI SARTGHHISF WQFTRYGIVV TVLSTVMAWV
YVWLRYFL
//
