ID A0A1Q4YSP7_9PSEU Unreviewed; 555 AA.
AC A0A1Q4YSP7;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=VWFA domain-containing protein {ECO:0000259|PROSITE:PS50234};
GN ORFNames=A6A25_18345 {ECO:0000313|EMBL:OKI37535.1};
OS Saccharothrix sp. CB00851.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharothrix.
OX NCBI_TaxID=1835005 {ECO:0000313|EMBL:OKI37535.1, ECO:0000313|Proteomes:UP000186828};
RN [1] {ECO:0000313|EMBL:OKI37535.1, ECO:0000313|Proteomes:UP000186828}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB00851 {ECO:0000313|EMBL:OKI37535.1,
RC ECO:0000313|Proteomes:UP000186828};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKI37535.1}.
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DR EMBL; LWLC01000003; OKI37535.1; -; Genomic_DNA.
DR RefSeq; WP_073886696.1; NZ_LWLC01000003.1.
DR AlphaFoldDB; A0A1Q4YSP7; -.
DR STRING; 1835005.A6A25_18345; -.
DR Proteomes; UP000186828; Unassembled WGS sequence.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProt.
DR CDD; cd01450; vWFA_subfamily_ECM; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR008964; Invasin/intimin_cell_adhesion.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR24020; COLLAGEN ALPHA; 1.
DR PANTHER; PTHR24020:SF84; COLLAGEN ALPHA-1(XXI) CHAIN-LIKE ISOFORM X1; 1.
DR Pfam; PF00092; VWA; 1.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF49373; Invasin/intimin cell-adhesion fragments; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000186828};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..555
FT /note="VWFA domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012637500"
FT DOMAIN 61..236
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
SQ SEQUENCE 555 AA; 55303 MW; 8E659DD6C3E7C116 CRC64;
MTAILLAALA APLATTTGAA AAGGTVNGAK TLGATDITCG GSVPVTVTLD AETGIAGNPV
DIELVLDRSG SMQGAIGDLK TAAKSFVDII DEATDGSLNG VVANGSRIGV VSFADGASVD
TPLSSDANAA KSAIDALVAS GGTNHSAAIT TGQSQLAGSE PTNEKIMVIM TDGQTTVGPD
ASPAAEAARN AGTEIFGIGL GSVDANEIRD WTTDPDSTHY YQAPTAAQLQ EVFEAIGAAI
VVPAATNVTV VDTVAPQFSV SGAAVSKGSV AQNGNQLTWT MAELGTETVT LTFTATHFPS
AGGGALAVNP TVAYTDAEGH VVTFGNPTVN VRGCAAAIDV EPEQETNELG TPGQTHTVTA
TVTDDFGDPV ANVPVDFSIL SGPNAGGTGN GGTSGTGTVD FTYPATQGLA GLGQDSIRGC
FTHAAGHQLC DDVLKDWVDT TPPVVTCQPT NNPGGGNVPP ADNEDGFFVL TATDAVDPNP
QLFVSDSASS AVFGGFPTGT KIKLVQAPGA TPNQKPGVGD IDWRITLNGD ALVYGVDASG
NQSAPVSCLV PPPPK
//
