ID A0A1Q4YVM3_9ACTN Unreviewed; 289 AA.
AC A0A1Q4YVM3;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 13.
DE SubName: Full=Serine hydrolase {ECO:0000313|EMBL:OKI38634.1};
GN ORFNames=A6A29_11045 {ECO:0000313|EMBL:OKI38634.1};
OS Streptomyces sp. TSRI0281.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1718998 {ECO:0000313|EMBL:OKI38634.1, ECO:0000313|Proteomes:UP000186952};
RN [1] {ECO:0000313|EMBL:OKI38634.1, ECO:0000313|Proteomes:UP000186952}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TSRI0281 {ECO:0000313|EMBL:OKI38634.1,
RC ECO:0000313|Proteomes:UP000186952};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKI38634.1}.
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DR EMBL; LWLE01000023; OKI38634.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Q4YVM3; -.
DR STRING; 1718998.A6A29_11045; -.
DR Proteomes; UP000186952; Unassembled WGS sequence.
DR GO; GO:0008800; F:beta-lactamase activity; IEA:InterPro.
DR GO; GO:0030655; P:beta-lactam antibiotic catabolic process; IEA:InterPro.
DR GO; GO:0046677; P:response to antibiotic; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR045155; Beta-lactam_cat.
DR InterPro; IPR000871; Beta-lactam_class-A.
DR PANTHER; PTHR35333; BETA-LACTAMASE; 1.
DR PANTHER; PTHR35333:SF4; SLR0121 PROTEIN; 1.
DR Pfam; PF13354; Beta-lactamase2; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:OKI38634.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000186952}.
FT DOMAIN 14..253
FT /note="Beta-lactamase class A catalytic"
FT /evidence="ECO:0000259|Pfam:PF13354"
SQ SEQUENCE 289 AA; 30385 MW; 15CE1572B6B02735 CRC64;
MRAAFAEAGV TGWLHAVDID SGAQIDAGAD RPVVTASVHK LCLLVALHQQ AEAGRLVLTE
QTECPRDGRT AGPTGLAAML DAARVSLRDA AYLMVAVSDN TAADLLLERV GLDAVNDTTR
RLGLTRTHAT QTFREFLATI REDAGNGGPQ ALADPQVVAR LRAVDPARTN RSTPRDMTRL
LGAIWRDEAC TPEHGAAIRR LLGLQVWPHR LASGFPFDDV LVAGKTGSAP TVRNEVGVVE
YPDGGRYAVA VFTRAASPAA TLPAADAVIG TAARIAVDAL RAPGPHATD
//
