ID A0A1Q4YXN4_9PSEU Unreviewed; 355 AA.
AC A0A1Q4YXN4;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=Nitric oxide synthase oxygenase {ECO:0000313|EMBL:OKI39342.1};
GN ORFNames=A6A25_04120 {ECO:0000313|EMBL:OKI39342.1};
OS Saccharothrix sp. CB00851.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharothrix.
OX NCBI_TaxID=1835005 {ECO:0000313|EMBL:OKI39342.1, ECO:0000313|Proteomes:UP000186828};
RN [1] {ECO:0000313|EMBL:OKI39342.1, ECO:0000313|Proteomes:UP000186828}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB00851 {ECO:0000313|EMBL:OKI39342.1,
RC ECO:0000313|Proteomes:UP000186828};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKI39342.1}.
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DR EMBL; LWLC01000001; OKI39342.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Q4YXN4; -.
DR STRING; 1835005.A6A25_04120; -.
DR Proteomes; UP000186828; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004517; F:nitric-oxide synthase activity; IEA:InterPro.
DR GO; GO:0006809; P:nitric oxide biosynthetic process; IEA:InterPro.
DR Gene3D; 3.90.440.10; Nitric Oxide Synthase;Heme Domain;Chain A domain 2; 1.
DR InterPro; IPR044943; NOS_dom_1.
DR InterPro; IPR044940; NOS_dom_2.
DR InterPro; IPR044944; NOS_dom_3.
DR InterPro; IPR004030; NOS_N.
DR InterPro; IPR036119; NOS_N_sf.
DR PANTHER; PTHR43410; NITRIC OXIDE SYNTHASE OXYGENASE; 1.
DR PANTHER; PTHR43410:SF1; NITRIC OXIDE SYNTHASE OXYGENASE; 1.
DR Pfam; PF02898; NO_synthase; 1.
DR SUPFAM; SSF56512; Nitric oxide (NO) synthase oxygenase domain; 1.
PE 4: Predicted;
KW Heme {ECO:0000256|ARBA:ARBA00022617}; Iron {ECO:0000256|ARBA:ARBA00023004};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000186828}.
FT DOMAIN 14..303
FT /note="Nitric oxide synthase (NOS)"
FT /evidence="ECO:0000259|Pfam:PF02898"
SQ SEQUENCE 355 AA; 39244 MW; 4B9AA140CCB5A42C CRC64;
MFHIAHPEAG PVGPRLSEVR DEIAETGTYR HTTHELAYGA RIALRDSGWC TSGVPWRRLK
VRDLRGFRNA GAVAAECVEH LRLATNGGEI RPLVTVFAPD TPTAPGPCIW NEQLVRYAGY
GDGTGDRRYR EFTDAVQGMG WRAPTPTGRF DLLPLVVETA HEGVRLFDVP PDVVHEVMLE
HPELPWFGRL GLRWHAVPVI TNMRLTIGGV TYPAAPFNSW FVGSEIGARS LADDHAYGAA
RPVAEALGLD TSTERSLWRD RAVVELNRAV LHSFDLASVT ITDHHAESRH RLSWLRSRQR
HSGNRPAFRL DPSVARRARA GGPARFAPAL AETTRPQSPG RLAELLRRRV EGAGG
//
