ID A0A1Q4ZB45_9ACTN Unreviewed; 493 AA.
AC A0A1Q4ZB45;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE SubName: Full=Aminodeoxychorismate synthase component I {ECO:0000313|EMBL:OKI43924.1};
GN ORFNames=A6A29_35555 {ECO:0000313|EMBL:OKI43924.1};
OS Streptomyces sp. TSRI0281.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1718998 {ECO:0000313|EMBL:OKI43924.1, ECO:0000313|Proteomes:UP000186952};
RN [1] {ECO:0000313|EMBL:OKI43924.1, ECO:0000313|Proteomes:UP000186952}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TSRI0281 {ECO:0000313|EMBL:OKI43924.1,
RC ECO:0000313|Proteomes:UP000186952};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKI43924.1}.
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DR EMBL; LWLE01000011; OKI43924.1; -; Genomic_DNA.
DR RefSeq; WP_073721002.1; NZ_LWLE01000011.1.
DR AlphaFoldDB; A0A1Q4ZB45; -.
DR STRING; 1718998.A6A29_35555; -.
DR OrthoDB; 3518032at2; -.
DR Proteomes; UP000186952; Unassembled WGS sequence.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR Gene3D; 3.60.120.10; Anthranilate synthase; 1.
DR InterPro; IPR005801; ADC_synthase.
DR InterPro; IPR019999; Anth_synth_I-like.
DR InterPro; IPR006805; Anth_synth_I_N.
DR InterPro; IPR015890; Chorismate_C.
DR PANTHER; PTHR11236; AMINOBENZOATE/ANTHRANILATE SYNTHASE; 1.
DR PANTHER; PTHR11236:SF9; ANTHRANILATE SYNTHASE COMPONENT 1; 1.
DR Pfam; PF04715; Anth_synt_I_N; 1.
DR Pfam; PF00425; Chorismate_bind; 1.
DR PRINTS; PR00095; ANTSNTHASEI.
DR SUPFAM; SSF56322; ADC synthase; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000186952}.
FT DOMAIN 23..174
FT /note="Anthranilate synthase component I N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04715"
FT DOMAIN 229..479
FT /note="Chorismate-utilising enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00425"
SQ SEQUENCE 493 AA; 54194 MW; 365ECADF83D89D66 CRC64;
MTLQAPAVGV GVTTRTRRLP PLDLLNAYRN LCGRFGPDEA YLLESAAGPL RDRKYQFTGF
GALLSLSVTG DAVRIEGRPA LARLLRERAG PLLTDVSGQG LRLRGTDDLW ALLRAAQGMF
DAQGSAERFR FGFLAYFGYD TARYVEELPY LIERNSALPD IHLVLHQGCV TTDLTDGGTE
LLLHESEHWP PLDVEEIAAL LVREPDAELP CFDDADPPPA TVTDDSDPEL FRADVERCLE
HIAVGDIYQV QIGHELTMRS EAAPLDVYRR LRQRNASPYM YMANVGGHCT IGASPELFVR
IEGGKVMMRP IAGTLPRTGT DDEAAARTLA QDPKEIAEHT MLVDLCRNDI GRICEADTLN
VPDQLVVERY SHVLHLVSTV EARVEAGEDS FDAIAALFPA GTMTGTPKIR AMEIIESVER
SRRGLYAGAL GLMDIGGYTN LALCIRTLFH HDGAYRTRAS AGIVADSRPE SEWRETLAKM
SAAYWAVTGK ELL
//
