ID A0A1Q4ZM75_9ACTN Unreviewed; 322 AA.
AC A0A1Q4ZM75;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=YihY/virulence factor BrkB family protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=A6A29_02500 {ECO:0000313|EMBL:OKI47952.1};
OS Streptomyces sp. TSRI0281.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1718998 {ECO:0000313|EMBL:OKI47952.1, ECO:0000313|Proteomes:UP000186952};
RN [1] {ECO:0000313|EMBL:OKI47952.1, ECO:0000313|Proteomes:UP000186952}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TSRI0281 {ECO:0000313|EMBL:OKI47952.1,
RC ECO:0000313|Proteomes:UP000186952};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKI47952.1}.
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DR EMBL; LWLE01000001; OKI47952.1; -; Genomic_DNA.
DR RefSeq; WP_073718245.1; NZ_LWLE01000001.1.
DR AlphaFoldDB; A0A1Q4ZM75; -.
DR STRING; 1718998.A6A29_02500; -.
DR OrthoDB; 4127374at2; -.
DR Proteomes; UP000186952; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR017039; Virul_fac_BrkB.
DR PANTHER; PTHR30213:SF1; INNER MEMBRANE PROTEIN YHJD; 1.
DR PANTHER; PTHR30213; UNCHARACTERIZED; 1.
DR Pfam; PF03631; Virul_fac_BrkB; 1.
DR PIRSF; PIRSF035875; RNase_BN; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000186952};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 37..64
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 92..115
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 144..165
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 185..208
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 220..242
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 254..277
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 284..322
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 322 AA; 33313 MW; 0B4DF9ECA57877E4 CRC64;
MDWLKKLPVI GPLVSRLMET HAWRSYETLE RVHWARLAAA ITFISFLALF PLIAVGAAIG
AALLSDKQLD KIENKITEQV PGISDQLGID NLVAHAGTVG VVAGALLLFT GIGWVGSLRD
CLRAVWEVDD AEEGNPVVRK LKDAGLLLGL GGAALATLAA SAVGSTAVGW TADQLGIPDH
GAGGVLLQVA ALVVAVVADF LLLLYLLTLL PGVEPPRRRL MVAGLLGAIG FELLKLLLGS
YMKGVASKSM YGAFGVPVAL LLWINFTAKL LLFCAAWTAT RSRSEQTEEA GEAGEAGGTG
EAAEAVSDGG SDGPGRAAAS AG
//
