ID A0A1Q5AS21_9ACTN Unreviewed; 272 AA.
AC A0A1Q5AS21;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE SubName: Full=3-methyl-2-oxobutanoate hydroxymethyltransferase {ECO:0000313|EMBL:OKI61867.1};
GN ORFNames=A6A27_27565 {ECO:0000313|EMBL:OKI61867.1};
OS Micromonospora sp. CB01531.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=1718947 {ECO:0000313|EMBL:OKI61867.1, ECO:0000313|Proteomes:UP000186700};
RN [1] {ECO:0000313|EMBL:OKI61867.1, ECO:0000313|Proteomes:UP000186700}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB01531 {ECO:0000313|EMBL:OKI61867.1,
RC ECO:0000313|Proteomes:UP000186700};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKI61867.1}.
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DR EMBL; LWLS01000073; OKI61867.1; -; Genomic_DNA.
DR RefSeq; WP_073836379.1; NZ_LWLS01000073.1.
DR AlphaFoldDB; A0A1Q5AS21; -.
DR STRING; 1718947.A6A27_27565; -.
DR OrthoDB; 9780430at2; -.
DR Proteomes; UP000186700; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd00377; ICL_PEPM; 1.
DR Gene3D; 3.20.20.60; Phosphoenolpyruvate-binding domains; 1.
DR InterPro; IPR039556; ICL/PEPM.
DR InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR InterPro; IPR040442; Pyrv_Kinase-like_dom_sf.
DR PANTHER; PTHR42905:SF16; CARBOXYPHOSPHONOENOLPYRUVATE PHOSPHONOMUTASE-LIKE PROTEIN (AFU_ORTHOLOGUE AFUA_5G07230); 1.
DR PANTHER; PTHR42905; PHOSPHOENOLPYRUVATE CARBOXYLASE; 1.
DR Pfam; PF13714; PEP_mutase; 1.
DR SUPFAM; SSF51621; Phosphoenolpyruvate/pyruvate domain; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000313|EMBL:OKI61867.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000186700};
KW Transferase {ECO:0000313|EMBL:OKI61867.1}.
SQ SEQUENCE 272 AA; 27282 MW; 83266A523BE220EB CRC64;
MNDHHSRALH FRSLHVPGEP LVLVNAWDAA SARIVAAAGA RAVATTSAGV AWSLGAPDGD
ALGRAAAVDL VRRVVAAVPL PVTADIESGY GDTADEVAVT IEAVVAAGAV GVNVEDAWHD
GEAPLRPVDE QCARLAAVRS AVDRAGVPLY VNARVDTFLR GAGGVPETVA RAKAYLAAGA
DGVFVPGTVD PATVAALVEA IPAPLNVLAG PGAPAVPQLA KLGVARVSLG SAVAEAAYAV
ARRAAVEALA TGTYGALADT LDYGTLNELM RG
//
