ID A0A1Q5AV14_9ACTN Unreviewed; 493 AA.
AC A0A1Q5AV14;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE SubName: Full=Polyprenyl glycosylphosphotransferase {ECO:0000313|EMBL:OKI62847.1};
GN ORFNames=A6A27_27010 {ECO:0000313|EMBL:OKI62847.1};
OS Micromonospora sp. CB01531.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=1718947 {ECO:0000313|EMBL:OKI62847.1, ECO:0000313|Proteomes:UP000186700};
RN [1] {ECO:0000313|EMBL:OKI62847.1, ECO:0000313|Proteomes:UP000186700}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB01531 {ECO:0000313|EMBL:OKI62847.1,
RC ECO:0000313|Proteomes:UP000186700};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the bacterial sugar transferase family.
CC {ECO:0000256|ARBA:ARBA00006464}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKI62847.1}.
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DR EMBL; LWLS01000071; OKI62847.1; -; Genomic_DNA.
DR RefSeq; WP_073835970.1; NZ_LWLS01000071.1.
DR AlphaFoldDB; A0A1Q5AV14; -.
DR STRING; 1718947.A6A27_27010; -.
DR OrthoDB; 9808602at2; -.
DR Proteomes; UP000186700; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR003362; Bact_transf.
DR InterPro; IPR017475; EPS_sugar_tfrase.
DR NCBIfam; TIGR03025; EPS_sugtrans; 1.
DR PANTHER; PTHR30576; COLANIC BIOSYNTHESIS UDP-GLUCOSE LIPID CARRIER TRANSFERASE; 1.
DR PANTHER; PTHR30576:SF10; SLL5057 PROTEIN; 1.
DR Pfam; PF02397; Bac_transf; 1.
DR Pfam; PF13727; CoA_binding_3; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000186700};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:OKI62847.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 30..53
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 65..82
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 103..121
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 127..148
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 306..326
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 300..487
FT /note="Bacterial sugar transferase"
FT /evidence="ECO:0000259|Pfam:PF02397"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 493 AA; 53312 MW; 3A16EFA012708A67 CRC64;
MISATLLTPV RTSSRPGGDR PGPTRAAERA YIGVLVVLDT TVLAAAILIA YLARFGDEPP
SGSKIPYVVV APALLLVWLI SLKAMRCYDD RVLGYGADEY RRVSSASLRL AGGIAIAGYI
ADVGVSRGFL AISFAVGAIG LEVARYAARK RLHRARDRGA GWSRKVLVVG DTAHVLELVH
TLRREPYAGY QVVGASIPDA LLAPVPQRLG DVPVVGSFRD IPEAATAIGA DTVAVTASGS
LTATRLRRLG WQLEGTGVDL VVAPALTDVA GPRIHTRPVA GLPLIHVEAP EFRGARKLVK
GLVDRSLSLL ALLLLLPVLV VIALAIKLDS RGPVLFRQVR VGQGGEEFDV FKFRTMVVNA
DDLLAELAAR NETDGLMFKM RDDPRVTRTG RLLRKWSLDE LPQLANVLLG QMSLVGPRPP
LPSEVARYDG DLARRLLVKP GMTGLWQVSG RSDLSWEDGI RLDLYYVENW SLAADLTILW
KTFGAVIHRR GAY
//
