ID A0A1Q5CDM4_9ACTN Unreviewed; 522 AA.
AC A0A1Q5CDM4;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE SubName: Full=5,10-methylene tetrahydromethanopterin reductase {ECO:0000313|EMBL:OKI81679.1};
GN ORFNames=A6A27_16455 {ECO:0000313|EMBL:OKI81679.1};
OS Micromonospora sp. CB01531.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=1718947 {ECO:0000313|EMBL:OKI81679.1, ECO:0000313|Proteomes:UP000186700};
RN [1] {ECO:0000313|EMBL:OKI81679.1, ECO:0000313|Proteomes:UP000186700}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB01531 {ECO:0000313|EMBL:OKI81679.1,
RC ECO:0000313|Proteomes:UP000186700};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKI81679.1}.
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DR EMBL; LWLS01000024; OKI81679.1; -; Genomic_DNA.
DR RefSeq; WP_073833524.1; NZ_LWLS01000024.1.
DR AlphaFoldDB; A0A1Q5CDM4; -.
DR STRING; 1718947.A6A27_16455; -.
DR OrthoDB; 9775082at2; -.
DR Proteomes; UP000186700; Unassembled WGS sequence.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR CDD; cd12108; Hr-like; 1.
DR CDD; cd01097; Tetrahydromethanopterin_reductase; 1.
DR Gene3D; 3.20.20.30; Luciferase-like domain; 1.
DR Gene3D; 1.20.120.520; nmb1532 protein domain like; 1.
DR InterPro; IPR012312; Hemerythrin-like.
DR InterPro; IPR011251; Luciferase-like_dom.
DR InterPro; IPR036661; Luciferase-like_sf.
DR PANTHER; PTHR43244; -; 1.
DR PANTHER; PTHR43244:SF1; 5,10-METHYLENETETRAHYDROMETHANOPTERIN REDUCTASE; 1.
DR Pfam; PF00296; Bac_luciferase; 1.
DR Pfam; PF01814; Hemerythrin; 1.
DR SUPFAM; SSF51679; Bacterial luciferase-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000186700}.
FT DOMAIN 17..233
FT /note="Luciferase-like"
FT /evidence="ECO:0000259|Pfam:PF00296"
FT DOMAIN 367..509
FT /note="Hemerythrin-like"
FT /evidence="ECO:0000259|Pfam:PF01814"
SQ SEQUENCE 522 AA; 56704 MW; 56389D5BA007EAA8 CRC64;
MTDYRHELAF GGFLTPTAGQ FEQVVALAKL CEQVNLDLVT FQDHPYQPGF LDTWTLMSYL
AAATSRIRLA GNVLNLPLRQ PVVLARSVAS LDLLTGGRVE LGLGAGAFWE AIEAVGGRRL
SPGQAVDALD EAIRVIREVW DVERRGMVRV EGTYHRVVGA KRGPAPAHPV EIWVGAYKPR
MLRLVGRAAD GWLPSLAYLS KGPDELPGMN ALIDEEAEAA GRDPRSVRRL LNVSGQFTRS
SAGFLSGPPE QWVEELAGLV LDHGIATFIL GADDPTAIQL FAREVAPAVR ELVAAERAEP
GTRPRAGEEA REAVEAGGAT ALTVAPTPDP GVRLTDHQLW DESTRPVAPP APAGHVYTPH
AQAVGAHLVD VHDHLRQELA QVRDLLEQVK RGVVSAGAAR AVLNQMTMRQ NNWTLGAYCA
AYCTVVTQHH GLEDNSIFPH LRRADPGLTP VLDRLEAEHV VIHDVVEGVD RALVDLIRNP
GDFTEVQKAV DILTDTLLSH LSYEEQNIVE PLARHGFYAG QV
//
