ID A0A1Q5CVY7_9ACTN Unreviewed; 385 AA.
AC A0A1Q5CVY7;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE RecName: Full=exo-alpha-sialidase {ECO:0000256|ARBA:ARBA00012733};
DE EC=3.2.1.18 {ECO:0000256|ARBA:ARBA00012733};
GN ORFNames=A6A27_14080 {ECO:0000313|EMBL:OKI87726.1};
OS Micromonospora sp. CB01531.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=1718947 {ECO:0000313|EMBL:OKI87726.1, ECO:0000313|Proteomes:UP000186700};
RN [1] {ECO:0000313|EMBL:OKI87726.1, ECO:0000313|Proteomes:UP000186700}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB01531 {ECO:0000313|EMBL:OKI87726.1,
RC ECO:0000313|Proteomes:UP000186700};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKI87726.1}.
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DR EMBL; LWLS01000002; OKI87726.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Q5CVY7; -.
DR STRING; 1718947.A6A27_14080; -.
DR Proteomes; UP000186700; Unassembled WGS sequence.
DR GO; GO:0004308; F:exo-alpha-sialidase activity; IEA:InterPro.
DR CDD; cd15482; Sialidase_non-viral; 1.
DR Gene3D; 2.120.10.10; -; 1.
DR InterPro; IPR011040; Sialidase.
DR InterPro; IPR026856; Sialidase_fam.
DR InterPro; IPR036278; Sialidase_sf.
DR PANTHER; PTHR10628; SIALIDASE; 1.
DR PANTHER; PTHR10628:SF25; SIALIDASE-1; 1.
DR Pfam; PF13088; BNR_2; 1.
DR SUPFAM; SSF50939; Sialidases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000186700};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 46..354
FT /note="Sialidase"
FT /evidence="ECO:0000259|Pfam:PF13088"
SQ SEQUENCE 385 AA; 39957 MW; 2360FA19C0AB926D CRC64;
MAVGAAPAAA APGGGPRHCD TSVPFVSGTE GYTAFRIPAV VTARSGTLLA FAEGRAGSLG
DAGNIDLVLK RSGDGGCTWG PLQVVHERGP DTAGNPAPVL TSAGRLVLLS TVNAGDASEA
EIMRGEVTPE QSRRVFVQYS DDEGASWSAP REITDQAKAS TWRWYATGPG HAVRLTVGAH
AGRLVVPANH SIAPPAGSPD LGTEAKYYGG HLLYSDDDGA SWQIGAVDDN PDGYLNVNES
TAAELPDGRL YLNSRDQNGS APGTRADTYS ADGGETLVQP YRPQATLVGP VVQGSVLRLA
GPHAPLLYSG PADPNSRAVM TLRTSTDQGA TWQPALALSG LPAGYSDLVQ LDNRTVGVLY
ETGNSGPYQT ITFRRVSVGD LRPGR
//
