ID A0A1Q5DG81_9ACTN Unreviewed; 712 AA.
AC A0A1Q5DG81;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Peptidase S9 {ECO:0000313|EMBL:OKI94791.1};
GN ORFNames=AMK18_28375 {ECO:0000313|EMBL:OKI94791.1};
OS Streptomyces sp. CB01249.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1703929 {ECO:0000313|EMBL:OKI94791.1, ECO:0000313|Proteomes:UP000186839};
RN [1] {ECO:0000313|EMBL:OKI94791.1, ECO:0000313|Proteomes:UP000186839}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB01249 {ECO:0000313|EMBL:OKI94791.1,
RC ECO:0000313|Proteomes:UP000186839};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKI94791.1}.
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DR EMBL; LISW01000008; OKI94791.1; -; Genomic_DNA.
DR RefSeq; WP_073865075.1; NZ_LISW01000008.1.
DR AlphaFoldDB; A0A1Q5DG81; -.
DR OrthoDB; 9812921at2; -.
DR Proteomes; UP000186839; Unassembled WGS sequence.
DR GO; GO:0008236; F:serine-type peptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 2.140.10.30; Dipeptidylpeptidase IV, N-terminal domain; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR001375; Peptidase_S9.
DR InterPro; IPR002469; Peptidase_S9B_N.
DR PANTHER; PTHR11731:SF193; DIPEPTIDYL PEPTIDASE 9; 1.
DR PANTHER; PTHR11731; PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED; 1.
DR Pfam; PF00930; DPPIV_N; 1.
DR Pfam; PF00326; Peptidase_S9; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF82171; DPP6 N-terminal domain-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000186839}.
FT DOMAIN 118..408
FT /note="Dipeptidylpeptidase IV N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00930"
FT DOMAIN 513..711
FT /note="Peptidase S9 prolyl oligopeptidase catalytic"
FT /evidence="ECO:0000259|Pfam:PF00326"
FT REGION 68..95
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 79..95
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 712 AA; 75913 MW; 8987ACCD60834E40 CRC64;
MTDPAASPAD PFPDQFARTR RFSLGVPRQF TVSPDGERIL FVRGTSGTDP VSRLWLYGNG
AERMLADPLG PGFTEEGPGE VPPEERARRE RAHETSSGVV SYATDASVNL AVLALAGALW
LVPTDGTAPR RLPTAGPAVD PRPSPDGSLI AYVSGGALRT VRADGTGDRA VAGPDGAHIT
YGLSDYVSQE SIGRTRGYWW SPRGDALLVA RTDTSGVRRR YLTDPAHPER PPRELAYPAA
GTPNAKVSLH LVRLSGERTP VRLPEAAGDG HPEAAWTDRA FEYVVAADWD DRGPLVSVQT
RDQRSVHVLA VDEATGDTTT VHRAHDPAWV ALRPGTPLRL PSGALVVPAH PGGDTQGLDI
GGAPTPPGLE VREVLGAADG RVYFTGGDEP TEVHVWSYDT AGGGPVRVSG VPGVHTAAVG
GPVVVLDSRT PDGHTVSVLR DGAEAGRIAV LAEEPLVVPR PLALSLGARE LRSRLYLPSW
HAPGDEPLPV LLSPYAGHGM QVVLKVRTWW TAVAQWFAEQ GFAVLVTDGR GTPGRGEAWE
KSVHGDRLTA VLDDQIDALH AVAADRPELD LTRVAMRGWS FSGYLAAAAV LRHPEVFHAA
VAGAAPADRR LYDTHWEERF LGHPDVLPEN YDRNSLLDEA ASLTRPLMLV HGLGDDNVTV
AHTLRLSSAL LAAGRPHTVL PLSGAGHLVG RDRTASGLLR LERDFLRRSL GV
//
