ID A0A1Q5DNS1_9ACTN Unreviewed; 297 AA.
AC A0A1Q5DNS1;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE SubName: Full=NADPH:quinone reductase {ECO:0000313|EMBL:OKI97498.1};
GN ORFNames=AMK10_01270 {ECO:0000313|EMBL:OKI97498.1};
OS Streptomyces sp. CB02058.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1703921 {ECO:0000313|EMBL:OKI97498.1, ECO:0000313|Proteomes:UP000185610};
RN [1] {ECO:0000313|EMBL:OKI97498.1, ECO:0000313|Proteomes:UP000185610}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB02058 {ECO:0000313|EMBL:OKI97498.1,
RC ECO:0000313|Proteomes:UP000185610};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKI97498.1}.
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DR EMBL; LIPG01000001; OKI97498.1; -; Genomic_DNA.
DR RefSeq; WP_073743918.1; NZ_LIPG01000001.1.
DR AlphaFoldDB; A0A1Q5DNS1; -.
DR OrthoDB; 9787435at2; -.
DR Proteomes; UP000185610; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd05289; MDR_like_2; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR44013; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C16A3.02C; 1.
DR PANTHER; PTHR44013:SF1; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C16A3.02C; 1.
DR Pfam; PF13602; ADH_zinc_N_2; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
FT DOMAIN 10..295
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 297 AA; 29465 MW; 04B900D07D1F5322 CRC64;
MRAVVVKTFG GPEAVELVET EVPVPGPGQV RIKVAAAAVN PVDAAYRAGF LVPLPEGGAL
GLGWDVAGTV DAVGAGAPFA AGAEVVALAY GPAPAKSHAE YVVVDGSAVA PAPASVDAVH
ASTVPLNTLT AAQALDLLDL APGSTLLVTG AAGGVGGYAV QLAHRAGISV AGVAGPGDEE
LVRSFGADRF VERGTAAGTF DAVLDAAVLG ADALAHVRDG GDYVGVIPQA GPPSVRGIRV
QVVEVAADGN RLAELVKLVD EGVLASRVAR TYPLERAAEA HARLAEGGVR GRLVLVP
//
