ID A0A1Q5DQ37_9ACTN Unreviewed; 196 AA.
AC A0A1Q5DQ37;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Malonic semialdehyde reductase {ECO:0000313|EMBL:OKI97973.1};
GN ORFNames=AMK10_03965 {ECO:0000313|EMBL:OKI97973.1};
OS Streptomyces sp. CB02058.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1703921 {ECO:0000313|EMBL:OKI97973.1, ECO:0000313|Proteomes:UP000185610};
RN [1] {ECO:0000313|EMBL:OKI97973.1, ECO:0000313|Proteomes:UP000185610}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB02058 {ECO:0000313|EMBL:OKI97973.1,
RC ECO:0000313|Proteomes:UP000185610};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKI97973.1}.
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DR EMBL; LIPG01000001; OKI97973.1; -; Genomic_DNA.
DR RefSeq; WP_073744767.1; NZ_LIPG01000001.1.
DR AlphaFoldDB; A0A1Q5DQ37; -.
DR OrthoDB; 9784375at2; -.
DR Proteomes; UP000185610; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd02148; RutE-like; 1.
DR Gene3D; 3.40.109.10; NADH Oxidase; 1.
DR InterPro; IPR029479; Nitroreductase.
DR InterPro; IPR000415; Nitroreductase-like.
DR InterPro; IPR023936; RutE-like.
DR PANTHER; PTHR43543; MALONIC SEMIALDEHYDE REDUCTASE RUTE-RELATED; 1.
DR PANTHER; PTHR43543:SF1; MALONIC SEMIALDEHYDE REDUCTASE RUTE-RELATED; 1.
DR Pfam; PF00881; Nitroreductase; 1.
DR SUPFAM; SSF55469; FMN-dependent nitroreductase-like; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW FMN {ECO:0000256|ARBA:ARBA00022643}; NADP {ECO:0000256|ARBA:ARBA00022857};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 15..174
FT /note="Nitroreductase"
FT /evidence="ECO:0000259|Pfam:PF00881"
SQ SEQUENCE 196 AA; 21499 MW; 2AE03741AE15A10E CRC64;
MSLVLDPAAQ DLLFREARTA NTFTDEPVTD EQVQAIYDLV KYGPTAFNQS PLRVVLVRSP
EARERLVAHM AEGNRPKTST APLVALLVAD HEFHEELPAL MPHFPQAKDA FFSERPVREQ
SAALNAALQA AYFIIGVRAA GLAAGPMTGY DAAGIEKEFL DGDHKLLMAV NIGKPGEDAW
FPRLPRLSYD EVVTTV
//
