ID A0A1Q5DWA9_9ACTN Unreviewed; 326 AA.
AC A0A1Q5DWA9;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=Transcriptional regulator {ECO:0000313|EMBL:OKJ00101.1};
GN ORFNames=AMK18_15605 {ECO:0000313|EMBL:OKJ00101.1};
OS Streptomyces sp. CB01249.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1703929 {ECO:0000313|EMBL:OKJ00101.1, ECO:0000313|Proteomes:UP000186839};
RN [1] {ECO:0000313|EMBL:OKJ00101.1, ECO:0000313|Proteomes:UP000186839}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB01249 {ECO:0000313|EMBL:OKJ00101.1,
RC ECO:0000313|Proteomes:UP000186839};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKJ00101.1}.
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DR EMBL; LISW01000003; OKJ00101.1; -; Genomic_DNA.
DR RefSeq; WP_073863280.1; NZ_LISW01000003.1.
DR AlphaFoldDB; A0A1Q5DWA9; -.
DR Proteomes; UP000186839; Unassembled WGS sequence.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR013196; HTH_11.
DR InterPro; IPR028349; PafC.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR InterPro; IPR026881; WYL_dom.
DR PANTHER; PTHR34580; -; 1.
DR PANTHER; PTHR34580:SF6; HTH DEOR-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF08279; HTH_11; 1.
DR Pfam; PF13280; WYL; 1.
DR PIRSF; PIRSF016838; PafC; 2.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000186839};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..326
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5013135258"
FT DOMAIN 6..60
FT /note="Helix-turn-helix type 11"
FT /evidence="ECO:0000259|Pfam:PF08279"
FT DOMAIN 140..318
FT /note="WYL"
FT /evidence="ECO:0000259|Pfam:PF13280"
SQ SEQUENCE 326 AA; 35122 MW; DDB5E3643DF0B788 CRC64;
MRAARLIRMV LLLQARPGMT AAELSRELAV SERTVTRDAQ ALSEAGVPVY AERGRAGGYR
LVGGYRTGLT GLARDEAEAL FLSGLPSALR EMGLADAASA ARLKVSAALT PALRDAPAGA
GRRFHLDAPG WYQEPVTPEL LPAVAEAVWR DRLLLARYWR AGRDSDVERE LAPYGLVLKA
GVWYLCARAG DDTRVYRIDR FTAASVSDTP FVRDEGFDLP AFWEERSAAF ARSLLRTEVR
LRLSEAGAHR LPHVADRAAA TEALEAAGPP GADGRVTVTL PVESLDVAYG QLLGLGPELE
VLEPTALRER FATAAARLHA LYGGAP
//
