ID A0A1Q5DXL6_9ACTN Unreviewed; 558 AA.
AC A0A1Q5DXL6;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Glycosyl transferase {ECO:0000313|EMBL:OKJ00570.1};
GN ORFNames=AMK18_18215 {ECO:0000313|EMBL:OKJ00570.1};
OS Streptomyces sp. CB01249.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1703929 {ECO:0000313|EMBL:OKJ00570.1, ECO:0000313|Proteomes:UP000186839};
RN [1] {ECO:0000313|EMBL:OKJ00570.1, ECO:0000313|Proteomes:UP000186839}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB01249 {ECO:0000313|EMBL:OKJ00570.1,
RC ECO:0000313|Proteomes:UP000186839};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKJ00570.1}.
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DR EMBL; LISW01000003; OKJ00570.1; -; Genomic_DNA.
DR RefSeq; WP_073863604.1; NZ_LISW01000003.1.
DR AlphaFoldDB; A0A1Q5DXL6; -.
DR Proteomes; UP000186839; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0044249; P:cellular biosynthetic process; IEA:UniProt.
DR GO; GO:1901576; P:organic substance biosynthetic process; IEA:UniProt.
DR GO; GO:0044238; P:primary metabolic process; IEA:UniProt.
DR CDD; cd06421; CESA_CelA_like; 1.
DR InterPro; IPR001173; Glyco_trans_2-like.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR43867:SF4; BETA-(1-3)-GLUCOSYL TRANSFERASE; 1.
DR PANTHER; PTHR43867; CELLULOSE SYNTHASE CATALYTIC SUBUNIT A [UDP-FORMING]; 1.
DR Pfam; PF13632; Glyco_trans_2_3; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000186839};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:OKJ00570.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 25..45
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 51..73
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 346..370
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 376..393
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 449..473
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 532..550
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 178..364
FT /note="Glycosyltransferase 2-like"
FT /evidence="ECO:0000259|Pfam:PF13632"
SQ SEQUENCE 558 AA; 61557 MW; D1B248FB14ACD71F CRC64;
MTVHHLPQPP SDRELYWYFG PQRRWVLISS SLAFVLTAAT MFTFALRTPA LWAFLAVLSL
NVVALALSSV NSLRARRLTR RSHEVLVHAW DPPELPTVDL YLPTCGEPLA VLDNAYRAVA
ALDWPDALTV WVLDDADSPE VAALAAAYGF RYVVRPDRGH LKKAGNLNHA LTLSSAEHIA
ILDADFAPRP DFLRHLVPYL ADPCVGIVQS PQCFDTDETM GWIQRAAGSA QEWFFRWIQP
SRDASDAAIC CGSNAVYRRS AIDRAGGFAR LDHSEDLYTG LALHAEGFRT LYVPVLVAKG
TSPDNLAAYL NQQYRWAMGN LHLLGTPVLK RMGAPWRMRL CFHEGIVGYL TTVVNTFAAP
LPPLVMMIWY PDHIRPWHVL PLLAPLWLWH VLLPRISRTR WRIEVIRANV LMSVAAGAAV
WHTLRGRSAA WVPTGAAGGG KSGALARRVV LVSLGWLVCS TSAAAAGLAL AVARNGWEPN
WGLGLYVLVQ LQINTPLIRD LLTELRPAAA PRPARAPRRP GTAVLPRRWP EALAVTATLV
LTALLASGWV NPMLPWLS
//
