ID A0A1Q5E1K7_9ACTN Unreviewed; 3037 AA.
AC A0A1Q5E1K7;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=DNRLRE domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=AMK18_10545 {ECO:0000313|EMBL:OKJ01856.1};
OS Streptomyces sp. CB01249.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1703929 {ECO:0000313|EMBL:OKJ01856.1, ECO:0000313|Proteomes:UP000186839};
RN [1] {ECO:0000313|EMBL:OKJ01856.1, ECO:0000313|Proteomes:UP000186839}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB01249 {ECO:0000313|EMBL:OKJ01856.1,
RC ECO:0000313|Proteomes:UP000186839};
RX PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL MBio 7:e02104-e02116(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OKJ01856.1}.
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DR EMBL; LISW01000002; OKJ01856.1; -; Genomic_DNA.
DR RefSeq; WP_073862634.1; NZ_LISW01000002.1.
DR OrthoDB; 4981820at2; -.
DR Proteomes; UP000186839; Unassembled WGS sequence.
DR CDD; cd00110; LamG; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 3.90.930.1; -; 1.
DR Gene3D; 3.40.570.10; Extracellular Endonuclease, subunit A; 1.
DR Gene3D; 2.180.10.10; RHS repeat-associated core; 3.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR044929; DNA/RNA_non-sp_Endonuclease_sf.
DR InterPro; IPR045351; DUF6531.
DR InterPro; IPR044927; Endonuclea_NS_2.
DR InterPro; IPR001791; Laminin_G.
DR InterPro; IPR022385; Rhs_assc_core.
DR InterPro; IPR031325; RHS_repeat.
DR InterPro; IPR006530; YD.
DR NCBIfam; NF033679; DNRLRE_dom; 1.
DR NCBIfam; TIGR03696; Rhs_assc_core; 1.
DR NCBIfam; TIGR01643; YD_repeat_2x; 10.
DR PANTHER; PTHR32305; -; 1.
DR PANTHER; PTHR32305:SF15; PROTEIN RHSA-RELATED; 1.
DR Pfam; PF20148; DUF6531; 1.
DR Pfam; PF13930; Endonuclea_NS_2; 1.
DR Pfam; PF13385; Laminin_G_3; 1.
DR Pfam; PF05593; RHS_repeat; 10.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000186839}.
FT DOMAIN 809..886
FT /note="DUF6531"
FT /evidence="ECO:0000259|Pfam:PF20148"
FT DOMAIN 2938..3015
FT /note="Type VII secretion system protein EssD-like"
FT /evidence="ECO:0000259|Pfam:PF13930"
FT REGION 57..168
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 818..846
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1445..1487
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1589..1625
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1870..1889
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1897..1958
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2053..2099
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2752..2798
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2850..2885
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 152..168
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1448..1473
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1897..1920
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1935..1949
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2776..2798
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2858..2881
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3037 AA; 320796 MW; EE7EB67B5A596D92 CRC64;
MPSRPRPRPH AVFRHAFAWR SSRVAALTAG SVLLALGATL LPPPALTPFA RAADAAAPWS
DTEAPTQRTG TAAGRDHEVG ADRTDATGRN GLDPADLEAG DGALPLHDGG NGFAPVEPEA
AQTALEPGTE STEEDGTTGY DPDESVEIPA ERTSTSKEFG NPDGTRTTRV YTEPVHYEDA
SGTWQDIDTS LVPANEAKGA PEAAKTDSDR LAAASDDTGL TLAPQGDDPA LARLTLDEGQ
HAVGFGLDGA SDTTAQVHGD TAHYAGIRPG ADVTLQATHG AVKETIVLDS ADAPHIWTFP
LDLDGLTPSL DEHGAVLLKD ADGAAQAVIP KGWMEDSSHD AETGGPALSG DVDYALTEKD
GRWSLKVELD DAWLDAPQRV YPVRVDPSVD DIDSNGDAFV QDSWPDSNFA GDDELKIGSY
DGGTNRAISY MRFNNVTSKL KHRYILNADL GLFNVWSSSC SAQKMTVNQV TGSWSSTTVT
WNNRPASLDH LVASDSFAYG ENCGGSKWRT IDLGNKGVDL VQGWVDGSIT NNGLAIWADF
DSSGPWKRFG SANSANKPYL SVTHSAYGAQ YTVGSQTAPL TGGQSGEVDV TVKNTGDFTW
EPQGWNEVRL GTRVRNFSTG ALMEQKAFTR LNERLTPGDD TTLSARIPPL PPGKYKINFD
VQRLRDQKWF STESVPVATV TVTSQDIGPR VTDVYPHPGG QVGSLTPTLF MDTETVDHYP
AGAAIDHYFE VCSGTAAKPT GCVNSGWQTK RTWNVPAAKL TWGKQYLWRV KARENGLATA
LSPFYTFTTA VEQPAITSHL GDQGPAGDGR EVDPGIGNYT TTDTDATVAT TGPGLTVSRT
YNSRDPRSDN AFGAGWTTRY DMRITPDGDG TGNVVATLPT GRQVRFGKNP DGSYAPPYGS
FSTLTSVTGG GWTLTDKDQT SYVFDGDGRL TQVTDYRDRA QTLAYNTSGE LTTVTAAGGR
ALHLTWSGGH VKTVTTDAPA TGANPLTWTY SYDGDRLTQV CGPEDTTGHC TAYSYGDGSH
HRTVVHDAGP FSYWRLDEKD GATDAASDLP LDRDEHAATY QDVQLGTAGA LKGSADTAAT
FNGTTSYVQL PDQLISDTPY LTAELWFRTT GSGVLLSYQD HTLEEATTGK NTPALYVGTD
GKLRGEFWNG KAAPITSATT VNDGTWHHAA LTAAGNTQTL YLDGKKAGSL SGDITQYDQR
FVYLGAGYWN GWAATTGTIG HLTGDIDEAA VYSRPLGAST IAQHHAAAQV AQQLTGVTLP
SGRVHSAVTY DTVYDRVSSY TDANGGDYKL SDLAPTGTDA KPATDDQDAT AGTTTLTVTV
TDPEKRTSAY TYDPLQGNRL ISQKDTADHT GTFAYDTGGF LAATTGPDGT VTRFGNDERG
NKVSQTTCRD AADEATCHTS YYAYYLNASD PLDPRNDQLT AVRDARSASA SDDTYKTAYG
YDAHGDRVST TTPATPDFPS GRTESSTFTD GTESAVGGGK VPAGLLADTT DARGGVTERA
YTAAGDLAEV TDPAGAVSRY AYDGLGRETA QTAVSDAQPD GVTTTTVYDG ESRPVTVTDP
AVTNAVTGEQ HRARTTYTYD ADGNVLTESV SDTVGGDPAR TTERGYDTHG RQKSETDPSG
ATGTSTYDVF GHRVAGTTAD GQSYAYAYTA LGAVAEVTLK DWKGDPNNPS DPVDKVIDSY
AYDPAGRLAE HTDAMGRTTR TTYYDDGLEA RQILTGFHDP DGTTRDLVLS EKKYDAAGNL
TSETTGNGTV TTAYEVDAAG RTTAEVLDPA GLARRTAYTF DASGAVLTET HTGAGGSRAE
KVTYERDITG EATRLTVENG DEDLVTTRTV DDRGLVLSET SARGNAPGAD AAAYTTDYGY
DALGRQTEAK APPVTAETRD GGASTVRPVT RTGYNAFGDP TDQQDPDGNV THTTYDGLGR
ETATTLPGYT PPGGSPLVTR TSRTYDSAGR PVTETDELGG VTTYTYDQLG NLAGVTRPAP
TEGADRPVTT MTNDLLGEQL SVTGPTGARS EATYDDLGRQ ITSTRLERTP APGAFTTTLT
YDDAGNLVAT KSPTGLTEGS EYNAAGEPVS QTDTAGKKTL HTYGPTGLTT STTTPQGRTT
RAGFDLAGRA VSASDEDATG KVLSTRSSTY DADGNPVTVT DALHHTVRQS YDALGRLTEL
VEPVDADTSI TTTFGYDAAG RRTRLTDGRG NTTWTTFTSH GQPESIVEPS TTADPAEADR
TWTTVYDAAG RPAEERQPGG VTQKRAFDAL GRVTEVTGSG AEAATVADRY GYDAAGNLTS
VSAPGGTDRY TYDDRGNLLT TSGPSGTATL SYDEEGHLTG RTDAAGHAVF GYDTAGRLAS
AADPLTATTL TYGYDNASRL TSVGYGASGA KRSFSYDALD RLTSDTLKAP GGATTAATGY
GYDEASRLVS ETTSGTAGDG EQDYAYDWAG RLTEWTAADG AKTPYGWDAA GNRTKAGTVT
ATYDARNRLL TAGDTSYSYS PRGTRTGSTE GGVTHTAAFD ALGRMITSDD TTYTYDGLGR
VVGRGDDTFA YADQSNNLVS GGGSLVVRDP AGDALATADP DGGNASAVLS DQHGDVTGRF
APATGELSGS SAYSPFGQVT ARTADGTGTL GYQGEYTDPD SGQVDMHARW YDPSTGGFSS
RDSWTLNPAP SGQANRYAYG AGSPLLNTDP SGHCLEDLCV GEAIVVSLLA GYVGSSISEY
YRQHPVHITW PSFSWPWSHS SSSATPSYTN IFGNSMSSTA SAIAAQAAAQ GAAARRNART
PVADHPSSPG YTPYRSPGRP QAPRPPGPPP PPPPPPWAQM IKAVLRVVQA RPTGSTDTDA
EHQRYVDDAF TRAQKDLNLT EEQLRGYFKL FPDGDVDSNP SSAPSPQPSP SAGNSSGAGD
PCSRSKEERF YYEPLVDGRP QGAIALICPQ DLKKPNQGRD DSGDPYVAGF PDPNPVDADG
LYIYNRTHIV ADRFGGEWRS ENLFTGYRLM NTSGMKRCEN KIAKQLQAGN PVLYSGQLTY
PNDSTKMPDA IHMTAVTKKG VLFNTPVANL QRKGNSC
//
