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Database: UniProt
Entry: A0A1Q5E327_9ACTN
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ID   A0A1Q5E327_9ACTN        Unreviewed;       318 AA.
AC   A0A1Q5E327;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   SubName: Full=Thioredoxin {ECO:0000313|EMBL:OKJ02504.1};
GN   ORFNames=AMK18_14015 {ECO:0000313|EMBL:OKJ02504.1};
OS   Streptomyces sp. CB01249.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1703929 {ECO:0000313|EMBL:OKJ02504.1, ECO:0000313|Proteomes:UP000186839};
RN   [1] {ECO:0000313|EMBL:OKJ02504.1, ECO:0000313|Proteomes:UP000186839}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CB01249 {ECO:0000313|EMBL:OKJ02504.1,
RC   ECO:0000313|Proteomes:UP000186839};
RX   PubMed=27999165; DOI=10.1128/mbio.02104-16;
RA   Yan X., Ge H., Huang T., Hindra, Yang D., Teng Q., Crnovcic I., Li X.,
RA   Rudolf J.D., Lohman J.R., Gansemans Y., Zhu X., Huang Y., Zhao L.X.,
RA   Jiang Y., Van Nieuwerburgh F., Rader C., Duan Y., Shen B.;
RT   "Strain Prioritization and Genome Mining for Enediyne Natural Products.";
RL   MBio 7:e02104-e02116(2016).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OKJ02504.1}.
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DR   EMBL; LISW01000002; OKJ02504.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Q5E327; -.
DR   OrthoDB; 5181746at2; -.
DR   Proteomes; UP000186839; Unassembled WGS sequence.
DR   CDD; cd02956; ybbN; 1.
DR   Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   InterPro; IPR017937; Thioredoxin_CS.
DR   InterPro; IPR013766; Thioredoxin_domain.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   PANTHER; PTHR45663; GEO12009P1; 1.
DR   PANTHER; PTHR45663:SF11; GEO12009P1; 1.
DR   Pfam; PF00085; Thioredoxin; 1.
DR   Pfam; PF14559; TPR_19; 1.
DR   Pfam; PF14561; TPR_20; 1.
DR   SUPFAM; SSF52833; Thioredoxin-like; 1.
DR   PROSITE; PS00194; THIOREDOXIN_1; 1.
DR   PROSITE; PS51352; THIOREDOXIN_2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000186839}.
FT   DOMAIN          32..150
FT                   /note="Thioredoxin"
FT                   /evidence="ECO:0000259|PROSITE:PS51352"
SQ   SEQUENCE   318 AA;  33609 MW;  DDCDA35690D4F386 CRC64;
     MSMSGVVDLA AVKAAGEAKA KAEQARAESA RQGGPAAVPA SSLVIDVNEA GFENDVLQRS
     AEVPVVIDFW AEWCEPCKQL GPLLERLARE YNGRFLLAKV DVDANQMLMQ QFGIQGIPAV
     FAVVAGQALP LFQGAAPEAQ IRQTLDQLIQ VGEERFGLTG IAVDPAAGEP AQAAAPVPPG
     PYDSLLEAAA QALDANDFAG AVQAYKNVLS DDPANTEAKL GLAQAELLAR VRATDPQKVR
     AEAAEKPGDA DAQLAAADLD LVGGHVEDAF GRLVETVRRT FGEDRDRVRL RLLDLFEVIG
     PEDPRVGAAR TALARVLF
//
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